Original Article
Chinese neonatal birth weight curve for different gestational age
Li Zhu, Rong Zhang, Shulian Zhang, Wenjing Shi, Weili Yan, Xiaoli Wang, Qin Lyu, Ling Liu, Qin Zhou, Quanfang Qiu, Xiaoying Li, Haiying He, Jimei Wang, Ruichun Li, Jiarong Lu, Zhaoqing Yin, Ping Su, Xinzhu Lin, Fang Guo, Hui Zhang, Shujun Li, Hua Xin, Yanqing Han, Hongyun Wang, Dongmei Chen, Zhankui Li, Huiqin Wang, Yinping Qiu, Huayan Liu, Jie Yang, Xiaoli Yang, Mingxia Li, Wenjing Li, Shuping Han, Bei Cao, Bin Yi, Yihui Zhang, Chao Chen
Published 2015-02-02
Cite as Chin J Pediatr, 2015, 53(2): 97-103. DOI: 10.3760/cma.j.issn.0578-1310.2015.02.007
Abstract
ObjectiveSince 1986, the reference of birth weight for gestational age has not been updated. The aim of this study was to set up Chinese neonatal network to investigate the current situation of birth weight in China, especially preterm birth weight, to develop the new reference for birth weight for gestational age and birth weight curve.
MethodA nationwide neonatology network was established in China. This survey was carried out in 63 hospitals of 23 provinces, municipalities and autonomous regions. We continuously collected the information of live births in participating hospitals during the study period of 2011-2014. Data describing birth weight and gestational age were collected prospectively. Newborn′s birth weight was measured by electronic scale within 2 hours after birth when baby was undressed. The evaluation of gestational age was based on the combination of mother′s last menstrual period, ultrasound in first trimester and gestational age estimation by gestational age scoring system. Statistical analysis: the growth curve was drawn by using LMSP method, which was conducted in GAMLSS 1.9-4 software package in R software 2.11.1.
ResultA total of 159 334 newborn infants were enrolled in this study. There were 84 447 male and 74 907 female. The mean birth weight was (3 232±555) g, the mean birth weight of male newborn was (3 271±576) g, the mean weight of female newborn was (3 188±528)g. The test of the variables′ distribution suggested that the distribution of gestational age and birth weight did not fit the normal distribution, the optimal distribution for them was BCT distribution. The Q-Q plot test and worm plot test suggested that this curve fitted the distribution optimally. The male and female neonatal birth weight curve was developed using the same method.
ConclusionUsing GAMLSS method to establish nationwide neonatal birth weight curve, and the first time to update the birth weight reference in recent 28 years.
Key words:
Infant, newborn; Birth weight; Growth charts; Reference standards
Contributor Information
Li Zhu
Chinese Neonatal Network. *Department of Neonatology, Children′s Hospital of Fudan University, Shanghai 201102, China
Rong Zhang
Shulian Zhang
Wenjing Shi
Weili Yan
Xiaoli Wang
Qin Lyu
Ling Liu
Qin Zhou
Quanfang Qiu
Xiaoying Li
Haiying He
Jimei Wang
Ruichun Li
Jiarong Lu
Zhaoqing Yin
Ping Su
Xinzhu Lin
Fang Guo
Hui Zhang
Shujun Li
Hua Xin
Yanqing Han
Hongyun Wang
Dongmei Chen
Zhankui Li
Huiqin Wang
Yinping Qiu
Huayan Liu
Jie Yang
Xiaoli Yang
Mingxia Li
Wenjing Li
Shuping Han
Bei Cao
Bin Yi
Yihui Zhang
Chao Chen
