Perinatal outcomes of dichorionic triamniotic triplet pregnancy
Zhou Ying, Jiao Yujie, Wei Yuan, Yuan Pengbo, Wang Xueju, Zhao Yangyu
Published 2020-11-25
Cite as Chin J Obstet Gynecol, 2020, 55(11): 764-769. DOI: 10.3760/cma.j.cn112141-20200422-00346
Abstract
ObjectiveTo analyze the perinatal outcomes in different methods of multifetal pregnancy reduction in dichorionic triamniotic (DCTA) triplet pregnancy.
MethodsA retrospective analysis was performed on 57 cases of DCTA triplets in Peking University Third Hospital from January 1, 2010 to January 1, 2020, including 27 cases in expectant pregnancy group and 30 cases in selective fetal reduction (FR) group. The selective FR group was further divided into 3 subgroups according to different FR methods:retaining monochorionic dichorionic (MCDA) group, retaining dichorionic dichorionic (DCDA) group, and retaining singleton group. The perinatal outcomes of expectant pregnancy group and 3 subgroups of selective FR group were compared.
ResultsThe gestational weeks in selective FR group was (34.5±5.7) weeks, and full-term delivery rate was 53% (16/30), respectively higher than those of the expectant pregnancy group (29.9±6.0) weeks and 7% (2/27). The miscarriage rate of the selective FR group was 10% (3/30), lower than that of the expectant pregnancy group (33%, 9/27). The differences between the two groups were statistically significant (all P<0.05). The ratios of pregnancy complications and newborn admission to neonatal ICU (NICU) in the selective FR group were lower than those of the expectant pregnancy group (allP<0.05). In the selective FR group, the gestational weeks in retaining MCDA group (6 cases), retaining DCDA group (13 cases), and retaining singleton group (11 cases) were (32.2±4.3), (33.0±6.3), and (37.4±4.7) weeks; the miscarriage rates were 1/6, 1/13, and 1/11; the premature delivery rates were 4/6, 7/13, and 0/11; the full-term delivery rates were 1/6, 5/13, and 10/11; pregnancies with at least 1 survivor rates were 5/6, 12/13, and 10/11; NICU occupancy rates were 6/8, 9/18 and 0/10, respectively. The retaining singleton group had the highest rate of full-term delivery and the lowest rate of NICU occupancy. Compared with other groups, the differences were statistically significant (allP<0.05). The full-term delivery rate was significantly higher in the retaining DCDA group than that of the expectant pregnancy group (P<0.05).
ConclusionsThe risk of DCTA triplet pregnancy is high. Reduction of the MCDA pair to singleton has the highest rate of full-term delivery and the lowest rate of NICU occupancy. For pregnant women who wish to retain twin pregnancy, the risk should be fully informed, and consider reduction of one fetus of the MCDA and retaining DCDA twins to continue pregnancy.
Key words:
Pregnancy, triplet; Pregnancy reduction, multifetal; Radiofrequency ablation; Pregnancy outcome
Contributor Information
Zhou Ying
Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China
Jiao Yujie
Department of Obstetrics, Tongzhou District Maternal and Child Health Hospital, Beijing 101100, China
Wei Yuan
Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China
Yuan Pengbo
Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China
Wang Xueju
Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China
Zhao Yangyu
Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China
