Fortum on Progress in Cariology and Endodontolgoy
Etiology and pathogenesis of internal root resorption
Yang Di, Qiu Lihong
Published 2022-01-09
Cite as Chin J Stomatol, 2022, 57(1): 38-43. DOI: 10.3760/cma.j.cn112144-20210929-00449
Abstract
Internal root resorption is a pathologic phenomenon with a characterization of the intraradicular dentin destruction due to the abnormal activities of odontoclasts. With its insidious pathology, internal root resorption can progress to a great extent before its clinical detection. The etiology and natural history of internal root resorption are uncertain and the associated key molecular pathogenesis have not been understood completely. The resorption is usually initiated by a stimulus with the loss of the protective predentin and progressed by the continuous stimuli of pulp infection. Various factors including trauma, chronic inflammation of the pulp, pulpotomy and tooth transplantation have been proposed for the occurrence of internal root resorption. The present paper reviews the etiology and pathogenesis of internal root resorption and provides guidance for the early intervention in the clinical practice.
Key words:
Root resorption; Internal root resorption; Odontoclast; Predentin; Tooth trauma; Pulpitis
Contributor Information
Yang Di
Department of Endodontics, School and Hospital of Stomatology, China Medical University &
Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang 110002, China
Qiu Lihong
Department of Endodontics, School and Hospital of Stomatology, China Medical University &
Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang 110002, China