Article
Classification of tracheobronchial tuberculosis in 252 children
Liu Fang, Rao Xiaochun, Ma Yuyan, Meng Chenfang, Pan Yuena, Liu Han, Shen Adong, Jiao Anxia
Published 2022-03-12
Cite as Chin J Tuberc Respir Dis, 2022, 45(3): 282-288. DOI: 10.3760/cma.j.cn112147-20210624-00444
Abstract
ObjectiveTo provide theoretical basis for early diagnosis and accurate bronchoscopic classification of tracheobronchial tuberculosis (TBTB) in children through analyzing the clinical characteristics, bronchoscopic classifications and treatment effect in children with TBTB.
MethodsIn this respective study, we collected clinical data of patients with TBTB who accepted bronchoscopies in Interventional Pulmonology Department of Beijing Children′s Hospital Affiliated to Capital Medical University between January, 2006 and December, 2019. The basic data, including clinical manifestations, imaging features, bronchoscopic characteristics and effects of interventional therapy were analyzed. The results of the study were statistically described and analyzed using SPSS 22.0 statistical software for relevant data.
ResultsTotal 252 children with TBTB were included in this study. The median age was 1.7 years (quartile: 0.8 years, 5.2 years). Analysis of the classification of TBTB showed that the percent of lymph node fistula type was 96.4% (243/252), ulcerative necrosis type 1.2%(3/252), granulation proliferation type 0.4% (1/252), and cicatricial stricture type 0.8% (2/252). In addition, 1.2% (3/252) of the cases showed the same bronchoscopic manifestations as lymph node fistula type, but it was not clear on imaging whether the caseous material in the lumen was caused by lymph node or lung erosion. Therefore, the "bronchial fistula type" was proposed.
ConclusionsLymph node fistula type of TBTB was the common in children. The classification of lymph node fistula mostly depended on imaging evidence, and this may lead to some uncertainty in classifying TBTB in cases with no imaging evidence of enlarged lymph nodes.
Key words:
Tuberculosis; Bronchoscopy; Classification; Children
Contributor Information
Liu Fang
Department of Interventional Pulmonology, Beijing Children′s Hospital, Capital Medical University, National Clinical Research Center for Respiratory Diseases, National Center for Children′s Health(NCCH), Beijing 100045, China
Rao Xiaochun
Department of Interventional Pulmonology, Beijing Children′s Hospital, Capital Medical University, National Clinical Research Center for Respiratory Diseases, National Center for Children′s Health(NCCH), Beijing 100045, China
Ma Yuyan
Department of Interventional Pulmonology, Beijing Children′s Hospital, Capital Medical University, National Clinical Research Center for Respiratory Diseases, National Center for Children′s Health(NCCH), Beijing 100045, China
Meng Chenfang
Department of Interventional Pulmonology, Beijing Children′s Hospital, Capital Medical University, National Clinical Research Center for Respiratory Diseases, National Center for Children′s Health(NCCH), Beijing 100045, China
Pan Yuena
Department of Interventional Pulmonology, Beijing Children′s Hospital, Capital Medical University, National Clinical Research Center for Respiratory Diseases, National Center for Children′s Health(NCCH), Beijing 100045, China
Liu Han
Imaging Center, Beijing Children′s Hospital, Capital Medical University, National Center for Children′s Health(NCCH), Beijing 100045, China
Shen Adong
Key Laboratory of Major Diseases in Children and National Key Discipline of Pediatrics (Capital Medical University), Ministry of Education, Beijing Key Laboratory of Pediatric Respiratory Infection Diseases, Beijing Pediatric Research Institute, Beijing Children′s Hospital, Capital Medical University, National Clinical Research Center for Respiratory Diseases, National Center for Children′s Health (NCCH), Beijing 100045, China
Jiao Anxia
Department of Interventional Pulmonology, Beijing Children′s Hospital, Capital Medical University, National Clinical Research Center for Respiratory Diseases, National Center for Children′s Health(NCCH), Beijing 100045, China
