Review
Research advances in the adverse effects of azo dyes
Deng Fuchang, Wang Chao, Gu Wen, Chen Yuanyuan, Han Jiajun, Du Huamao, Peng Hui, Tang Song
Published 2020-12-06
Cite as Chin J Prev Med, 2020, 54(12): 1478-1483. DOI: 10.3760/cma.j.cn112150-20200114-00020
Abstract
China is the world′s largest producer and user of dyes. The mass production and widespread use of disperse azo dyes led to environmental pollutions and potential human health risks. Azo dyes in environmental media (i.e., water, soil, air, and dust), food and clothing can enter the human body through multiple exposure routes, and some of them can be metabolized to produce more toxic metabolites, which can trigger toxic effects such as allergic reactions, tumor formation, and endocrine disruptions. This study systematically reviewed the production and use of azo dyes, environmental concentrations, human exposures, toxic effects and their underlying mechanisms, and regulations and standards. Meanwhile, the research trends of azo dyes were also discussed.
Key words:
Toxic actions; Carcinogens, environmental; Endocrine disruption; Disperse dyes
Contributor Information
Deng Fuchang
China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China
Wang Chao
China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China
Gu Wen
China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China
Chen Yuanyuan
China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China
Han Jiajun
Department of Chemistry, University of Toronto, ON M5S3H6, Canada
Du Huamao
College of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, China
Peng Hui
Department of Chemistry, University of Toronto, ON M5S3H6, Canada
Tang Song
China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China
