Review
Brief introduction of the application of microsimulation model in the primary and secondary cancer prevention
Lu Bin, Lu Ming, Zhang Yuhan, Cai Jie, Chen Hongda, Dai Min
Published 2021-10-06
Cite as Chin J Prev Med, 2021, 55(10): 1250-1255. DOI: 10.3760/cma.j.cn112150-20210118-00047
Abstract
Microsimulation model research can simulate a large number of micro individuals with different characteristics, build disease progression models, and evaluate the effects and benefits of risk factor control and early intervention strategies used in disease prevention and control, which could overcome the limitations of traditional epidemiological research, such as high investment and long time-consuming, and provide important evidence support for decision-making. This study introduces the definition and methods of microsimulation model, and articulates the application of three modeling methods including Markov model, decision-tree model and discrete event model in the primary and secondary cancer prevention, in order to provide reference for relevant disease prevention and control research in the future.
Key words:
Neoplasms; Primary prevention; Secondary prevention; Microsimulation model
Contributor Information
Lu Bin
Office of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Lu Ming
Office of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Zhang Yuhan
Office of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Cai Jie
Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
Chen Hongda
Office of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Dai Min
Office of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China