Surveillance and Trends
Bladder cancer incidence, mortality and temporal trends in China
Li Huizhang, Zheng Rongshou, Du Lingbin, Zhang Siwei, Zhu Chen, Wei Wenqiang, He Jie
Published 2021-03-23
Cite as Chin J Oncol, 2021, 43(3): 293-298. DOI: 10.3760/cma.j.cn112152-20200421-00362
Abstract
ObjectiveTo describe the epidemiological characteristics of bladder cancer in 2015 and temporal trends in China.
MethodsFrom 501 cancer registries in China, we collected data of cancer new cases, deaths and populations in 2015. After qualified, sex-specific, area-specific, age-specific and overall incidence/mortality rates (including age-standardized rates by Chinese standard population and by world standard population) and estimated cases of bladder cancer were calculated. Annual Percent Change (APC)/Average Annual Percent Change (AAPC) fitted from Log-line model was applied to evaluate the temporal trends of bladder cancer incidence/mortality rates from 1998 to 2015.
ResultsBladder cancer is the 13th most common cancer in China. The crude, age-standardized by China standard population and by world standard population rates were 5.80/105, 3.60/105 and 3.57/105 for incidence, and 2.37/105, 1.31/105 and 1.32/105 for mortality, respectively. The incidence of bladder cancer ranked 7th in male. The incidence and mortality of male were 3.8 and 4.0 times as high as those of female. Bladder cancer incidence in urban area was 1.4 times as high as that in rural area. Incidence in western areas and middle areas of China were similar, which were lower than that in eastern areas. Geographical distribution characteristics of mortality was along with incidence.Both incidence and mortality remained low before 45 and 55 years old, then they increased rapidly and peaked at 80-84 and over 85 years old age group. Temporal trend analysis suggested that bladder cancer incidence in China increased in 1998-2007 (APC=2.58, P<0.001), while decreased from 2007 to 2015 (APC=-3.82,P<0.001). Bladder cancer mortality declined gradually, with APCs for 1998-2003 and 2003-2015 of 3.65% (P=0.002) and 1.42% (P<0.001).
ConclusionsBladder cancer is one of the main cancers in China. Its epidemiological distributions varies among different sex, area and age group. Both incidence and mortality of bladder cancer decline. More efforts on tobacco control should be made, and awareness of early diagnosis and early treatment could be enhanced for the middle-aged and elderly.
Key words:
Cancer registry; Bladder neoplasms; Incidence rate; Mortality rate
Contributor Information
Li Huizhang
Department of Cancer Prevention (DCP), Cancer Hospital of University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Cancer Research and Basic Medical Sciences, Chinese Academy of Sciences, Hangzhou 310004, China
Zheng Rongshou
Office for Cancer Registry, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Du Lingbin
Department of Cancer Prevention (DCP), Cancer Hospital of University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Cancer Research and Basic Medical Sciences, Chinese Academy of Sciences, Hangzhou 310004, China
Zhang Siwei
Office for Cancer Registry, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Zhu Chen
Department of Cancer Prevention (DCP), Cancer Hospital of University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Cancer Research and Basic Medical Sciences, Chinese Academy of Sciences, Hangzhou 310004, China
Wei Wenqiang
Office for Cancer Registry, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
He Jie
Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
