In 1952, inspired by the "tissue therapy" which was being carried out nationwide at that time, Yu Changshi, a folk science enthusiast, proposed "chicken blood therapy" . In 1959, it was supported as an important achievement in technological innovation and technological revolution movement. In the following years, some researchers and many hospitals organized by the leaders of Jing’an District of Shanghai successively carried out the animal experiment, the first phase clinical experiment and the second phase clinical experiment of this therapy, and this therapy was also widely spread during this period.However, the expert meeting in 1965 gave it a basically negative conclusion on the basis of insecurity and poor long-term effect.