Imaging Technology
Preliminary imaging study on the distribution of female Volumetric Breast Density
Wang Jiahao, Qiu Rui, Hu Ankang, Kang Tianliang, Feng Zechen, Niu Yantao, Li Junli
Published 2022-10-25
Cite as Chin J Radiol Med Prot, 2022, 42(10): 806-811. DOI: 10.3760/cma.j.cn112271-20220527-00229
Abstract
ObjectiveTo describe the distribution of volumetric breast density(VBD) in different ages of Chinese women based on X-ray mammograms.
MethodsBased on mammographic images of 1 140 patients from January 2010 to December 2016 in a hospital in Beijing, the VBD of women was assessed by Volpara 1.5.1 and graded according to breast imaging reporting and data system published by American College of Radiology. The patients were divided into two groups according to the median age, and the two independent samples t-test was used to compare them. The patients were also divided into four groups according to age ( <40 years, 40-49 years, 50-59 years, ≥ 60 years), and the breast thickness, breast volume, glandular volume, and VBD were compared using a One-way ANOVA analysis.
ResultsThe median age was 50 years. The compressed breast thickness and breast volume in patients over 50 years were significantly higher than those in patients below 50 years (t= -8.99, -7.92, P<0.001), while glandular volume and VBD were significantly lower than those below 50 years (t= 8.11, 18.49, P<0.001). The compressed breast thickness, breast volume, glandular volume, and VBD were statistically significant different among four groups (F=27.10, 22.34, 25.70, 122.03, P<0.001). Patients over 60 years had the lowest VBD (t=-12.56, -15.27, -4.57, P<0.001). VBD was negatively correlated with ages (r=0.47, P<0.001).
ConclusionsThe compressed breast thickness and breast volume increased with ages, while the glandular volume and VBD decreased with ages.
Key words:
Mammography; Volumetric breast density; Glandularity
Contributor Information
Wang Jiahao
Key Laboratory of Particle &
Radiation Imaging, Department of Engineering Physics, Tsinghua University, Beijing 100084, China
Qiu Rui
Key Laboratory of Particle &
Radiation Imaging, Department of Engineering Physics, Tsinghua University, Beijing 100084, China
Hu Ankang
Key Laboratory of Particle &
Radiation Imaging, Department of Engineering Physics, Tsinghua University, Beijing 100084, China
Kang Tianliang
Department of Radiology, Beijing Tongren Hospital, Captial Medical University, Beijing 100730, China
Feng Zechen
Institute of Radiological Protection, Beijing Center for Disease Prevention and Control, Beijing 100013, China
Niu Yantao
Department of Radiology, Beijing Tongren Hospital, Captial Medical University, Beijing 100730, China
Li Junli
Key Laboratory of Particle &
Radiation Imaging, Department of Engineering Physics, Tsinghua University, Beijing 100084, China
