Prevention and Control of Hepatitis B
Estimation of incidence of viral hepatitis B and analysis on case characteristics in China,2013-2020
Miao Ning, Wang Fuzhen, Zheng Hui, Zhang Guomin, Yin Zundong
Published 2021-09-10
Cite as Chin J Epidemiol, 2021, 42(9): 1527-1531. DOI: 10.3760/cma.j.cn112338-20210319-00227
Abstract
ObjectiveTo understand the epidemiological characteristics of hepatitis B in China, evaluate the performance of elimination hepatitis B in China and provide scientific evidence for the prevention and control of hepatitis B.
MethodsAn analysis was conducted by using the data of hepatitis B cases reported to the National Notifiable Disease Reporting System (NNDRS) from the areas with low, moderate and high hepatitis B prevalence in China from 2013 to 2020, and the information about the diagnoses of the hepatitis B cases were collected, the incidence of hepatitis B was estimated according to the reporting and diagnosis information and the characteristics of acute and chronic hepatitis B were compared.
ResultsA total of 27 013 hepatitis B cases were reported to NNDRS, including 4 070 acute cases, 21 971 chronic cases and 972 unclassified cases. Among the reported acute hepatitis B cases, 69.9% (2 845/4 070) were confirmed. Among the reported chronic hepatitis B cases, 89.0% (19 548/21 971) were confirmed, and 2.1% (452/21 971) were confirmed as acute cases. It was estimated that the incidence of acute hepatitis B was 4.6/100 000 and the incidence of chronic hepatitis B cases was 54.5/100 000. The case number of acute hepatitis B in age group 31-45 years was highest, accounting for 35.3% (1 164/3 297). The case number of acute hepatitis B in children under 15 years old was lowest, accounting for 0.4% (13/3 297). The case number of chronic hepatitis B in age group 46-60 years was highest, accounting for 34.4% (7 211/20 932).
ConclusionsThe incidence of acute hepatitis B was in decrease and the incidence of chronic of hepatitis B was in increase in China year by year. It is important to strengthen the standardized diagnosis and treatment of chronic hepatitis B to decrease the morbidity and mortality of hepatitis B. At the same time, it is necessary to standardize the management and reporting of hepatitis B cases reported to NNDRS to improve the accuracy of the reporting of hepatitis B.
Key words:
Hepatitis B; Incidence; Estimate; Characteristics
Contributor Information
Miao Ning
Department of National Immunization Program, Chinese Center for Disease Control and Prevention, Beijing 100050, China
Wang Fuzhen
Department of National Immunization Program, Chinese Center for Disease Control and Prevention, Beijing 100050, China
Zheng Hui
Department of National Immunization Program, Chinese Center for Disease Control and Prevention, Beijing 100050, China
Zhang Guomin
Department of National Immunization Program, Chinese Center for Disease Control and Prevention, Beijing 100050, China
Yin Zundong
Department of National Immunization Program, Chinese Center for Disease Control and Prevention, Beijing 100050, China
