Review
Progress in research on immune escape mechanisms of influenza virus
Huang Mengting, Zhang Sen, Li Jing, Jiang Tao
Published 2020-12-30
Cite as Chinese J Exp Clin Virol, 2020, 34(6): 671-676. DOI: 10.3760/cma.j.cn112866-20191223-00204
Abstract
Influenza is a contagious respiratory illness caused by influenza viruses that can result in seasonal epidemics and global influenza pandemic, which poses a serious public health challenges world-wide. The pathogenicity of influenza virus depends to a great extent on viral virulence and its immune escape. This review provides an overview of the current understanding for the mechanisms by which influenza viruses to escape the host′s immune response, which will facilitate the future studies on influenza pathogenesis and the development of anti-influenza therapeutics.
Key words:
Influenza virus; Immune escape; Innate immune; Adaptive immune
Contributor Information
Huang Mengting
Anhui Medical University, Hefei 230032, China
State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China
Zhang Sen
State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China
Li Jing
State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China
Jiang Tao
Anhui Medical University, Hefei 230032, China
State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China
