Review
Recent advances in mismatch negativity of schizophrenia
Xu Shuqi, Wan Jinling, Ma Jinsheng, Wang Xueyi, Wang Ran
Published 2021-08-05
Cite as Chin J Psychiatry, 2021, 54(4): 300-304. DOI: 10.3760/cma.j.cn113661-20200922-00412
Abstract
Mismatch negativity (MMN) is an endogenous component of event-related potential that occurs with deviation stimulus. It has been widely used as a biomarker in schizophrenia-related researh. Studies have shown that MMN is correlated with early diagnosis of mental illness, cognitive impairment, and social-behavioral dysfunction in psychiatric patients. Further studies on relevant mechanisms would be conducive to understand the electrophysiological, cognitive, and behavioral changes of mental diseases and provide a new treatment strategy. This review introduces the latest progress in basic research and clinical application of MMN in schizophrenia, discusses the future research direction of MMN, and provides evidence for further research.
Key words:
Schizophrenia; Evoked potentials; Mismatch negativity
Contributor Information
Xu Shuqi
Department of Psychiatry, the First Hospital of Hebei Medical University, the Mental Health Institute of Hebei Province, the Mental Health Center of Hebei Medical University, Hebei Brain Ageing and Cognitive Neuroscience Laboratory, Hebei Key Laboratory of Brain Science and Psychiatric-Psychologic Disease, Shijiazhuang 050031, China
Wan Jinling
Department of Psychiatry, the First Hospital of Hebei Medical University, the Mental Health Institute of Hebei Province, the Mental Health Center of Hebei Medical University, Hebei Brain Ageing and Cognitive Neuroscience Laboratory, Hebei Key Laboratory of Brain Science and Psychiatric-Psychologic Disease, Shijiazhuang 050031, China
Ma Jinsheng
Department of Psychiatry, the First Hospital of Hebei Medical University, the Mental Health Institute of Hebei Province, the Mental Health Center of Hebei Medical University, Hebei Brain Ageing and Cognitive Neuroscience Laboratory, Hebei Key Laboratory of Brain Science and Psychiatric-Psychologic Disease, Shijiazhuang 050031, China
Wang Xueyi
Department of Psychiatry, the First Hospital of Hebei Medical University, the Mental Health Institute of Hebei Province, the Mental Health Center of Hebei Medical University, Hebei Brain Ageing and Cognitive Neuroscience Laboratory, Hebei Key Laboratory of Brain Science and Psychiatric-Psychologic Disease, Shijiazhuang 050031, China
Wang Ran
Department of Psychiatry, the First Hospital of Hebei Medical University, the Mental Health Institute of Hebei Province, the Mental Health Center of Hebei Medical University, Hebei Brain Ageing and Cognitive Neuroscience Laboratory, Hebei Key Laboratory of Brain Science and Psychiatric-Psychologic Disease, Shijiazhuang 050031, China
