Public Mental Health
Study on evaluation of different diagnostic criteria for metabolic syndrome applied in the population with alcohol use
Wang Ran, Xu Shuqi, Wang Lan, Zhao Ranran, Wang Xueyi
Published 2022-08-05
Cite as Chin J Psychiatry, 2022, 55(4): 288-294. DOI: 10.3760/cma.j.cn113661-20220104-00001
Abstract
ObjectiveTo evaluate four different diagnostic criteria for metabolic syndrome(MetS) in the Chinese Northern Population with alcohol use.
MethodsStratified random sampling was used to select male workers in Gaocheng District, Shijiazhuang in 2016. Alcohol Use Disorder Identification Test (AUDIT) was used to assess the risk of any alcohol use disorder. MetS-related physician and laboratory tests were performed. The MetS prevalence rate was calculated according to the diagnostic criteria of the Chinese Diabetes Society (CDS), the National Cholesterol Education Program (NCEP) Adult Treatment Panel-Ⅲ (ATP-Ⅲ), International Diabetes Federation (IDF), and the 2016 Chinese Adult Dyslipidemia Prevention and Control Guidelines, respectively. The CDS criteria were considered the reference standards for evaluating the significance of the other three MetS diagnostic criteria in disease screening.
ResultsA total of 1 267 men workers were investigated with a questionnaire, including 1 082 people with alcohol intake. The average age was (35.25±9.48) years. The MetS prevalence rates were 12.94%, 19.96%, 23.75%, and 23.94% according to CDS, NCEP ATP-Ⅲ, IDF, and Chinese Adult Dyslipidemia Prevention and Control Guidelines, respectively. In IDF, the highest prevalence rate of MetS was 18-25 and 35-45 age group; In the 45-68 age group, the highest and most consistent prevalence rate was found on MetS diagnostic criteria of IDF and Chinese Adult Dyslipidemia Prevention and Control Guidelines. MetS prevalence increased with drinking risk in all diagnostic criteria, and the MetS prevalence rate based on the IDF and Chinese Adult Dyslipidemia Prevention and Control Guidelines were higher than the other two. Referring to the CDS, the sensitivities of IDF,NCEP ATP-Ⅲ and Chinese Adult Dyslipidemia Prevention and Control Guidelines were 84.29%, 87.14%, and 92.14%; the specificities were 97.33%, 97.92%, and 98.66%, the positive predictive values were 45.91%, 56.48%, and 49.81%, respectively. Kappa consistency test found that IDF and Chinese Adult Dyslipidemia Prevention and Control Guidelines had the best consistency in total alcohol used population, lower-risk alcohol used population and lower-risk alcohol used population, with the compliance rate of 90.3%(Kappa=0.852),89.7%(Kappa=0.844) and 91.0%(Kappa=0.867).
ConclusionThe MetS prevalence rate in the alcohol use population in northern China varies by four diagnostic criteria. The MetS prevalence rate is the lowest on CDS, and the Chinese Adult Dyslipidemia Prevention and Control Guidelines give the highest MetS prevalence rate with the best sensitivity and specificity for diagnosing the MetS.
Key words:
Metabolic syndrome; Alcohol use; Diagnostic criteria; Prevalence rate
Contributor Information
Wang Ran
Department of Psychiatry, the First Hospital of Hebei Medical University, Shijiazhuang 050031, China
Xu Shuqi
Department of Psychiatry, the First Hospital of Hebei Medical University, Shijiazhuang 050031, China
Wang Lan
Department of Psychiatry, the First Hospital of Hebei Medical University, Shijiazhuang 050031, China
Zhao Ranran
Department of Psychiatry, the First Hospital of Hebei Medical University, Shijiazhuang 050031, China
Wang Xueyi
Department of Psychiatry, the First Hospital of Hebei Medical University, Shijiazhuang 050031, China
