Consensus
Chinese experts′ consensus on the treatment of essential tremor by deep brain stimulation
Chinese Society of Parkinson′s Disease and Movement Disorders, Parkinson′s Disease and Movement Disorder Section of Neurologist Branch of Chinese Medical Doctor Association, Neurophysiology Group of Neurosurgery Branch of Chinese Medical Association, Neurodegenerative Disease Branch of Chinese Neuroscience Society
Published 2021-12-08
Cite as Chin J Neurol, 2021, 54(12): 1225-1233. DOI: 10.3760/cma.j.cn113694-20210518-00345
Abstract
Essential tremor (ET), also known as idiopathic tremor, is mainly characterized by 4-12 Hz motor tremor of both upper limbs, with or without tremor of head, orofacial, voice or lower limbs. The pathogenesis of the disease is not completely clear. The rhythmic oscillation of cortical pontine cerebellar thalamus cortical circuit is the main pathophysiological mechanism of ET. At present, the treatment methods of ET mainly include drug treatment (oral drug and injection of botulinum toxin A), surgical treatment and rehabilitation treatment. About 1/3 of ET patients have poor response to drug treatment. Nowadays, deep brain stimulation (DBS) has become the first choice for the treatment of drug-resistant ET. Many centers in China have carried out DBS in the treatment of drug-resistant ET patients, but there is no specific guide or consensus at home and abroad. In order to further standardize the indications and process of DBS in the treatment of ET in China, further strengthen the close cooperation between neurology and neurosurgery, and improve the level of diagnosis and treatment, experts in relevant fields have formulated this consensus after full discussion.
Key words:
Essential tremor; Deep brain stimulation; Expert consensus
Contributor Information
Chinese Society of Parkinson′s Disease and Movement Disorders
Parkinson′s Disease and Movement Disorder Section of Neurologist Branch of Chinese Medical Doctor Association
Neurophysiology Group of Neurosurgery Branch of Chinese Medical Association
Neurodegenerative Disease Branch of Chinese Neuroscience Society