Long-term follow up outcomes of surgical resection of Shamblin Ⅱ/Ⅲ carotid body tumor: a single center analysis
Zhang Wei, Liu Fei, Wang Lixin, Guo Daqiao, Xu Xin, Chen Bin, Jiang Junhao, Yang Jue, Shi Zhenyu, Fu Weiguo
Published 2020-03-25
Cite as Chin J Gen Surg, 2020, 35(3): 195-198. DOI: 10.3760/cma.j.cn113855-20191209-00724
Abstract
ObjectiveTo evaluate the correlation between tumor size and surgical outcomes of Shamblin Ⅱ/Ⅲ carotid body tumor (CBT) and the prognosis.
MethodsFrom Apr 2011 to Dec 2017, 88 patients with Shamblin Ⅱ and Ⅲ CBTs undergoing tumor resection were retrospectively analyzed. The long-term prognosis of surgical resection was also evaluated.
ResultsOne patient died of multi-organ failure postoperatively, two patients abandoned surgery. The perioperative mortality was 1%. 85 patients having 87 lesions successfully resected were analyzed. There were 13 Shamblin Ⅱ and 74 Shamblin Ⅲ CBTs resection. Two patients had bilateral CBTs resection. The median of tumor size, procedural blood loss, procedural time, and length of hospital stay was 3.0 (1.2-5.5) cm, 200 (0-2 500) ml, 162 (85-430) min, and 10 (6-28) d, respectively. Seventy-two patients had carotid vascular intervention during the procedure, and thirty-three patients had neurological complications after the procedure. Correlation analysis showed that the tumor size had positive relationship with blood loss (Spearman R=0.35, P<0.01) and procedural time (SpearmanR= 0.54, P<0.01). Tumor size was positively associated with the risk of cranial neurological complication (OR=1.72, 95% CI 1.08-2.73, P=0.02) and carotid vascular intervention (OR=2.69, 95% CI 1.27-5.69, P=0.01). There were four patients who were diagnosed with malignant CBT due to the metastasis. Three suffered CBT recurrence after 1, 5, and 7 years during the follow up.
ConclusionsShamblin Ⅱ or Ⅲ CBTs should be intervened as early as possible to facilitate the surgical resection, as well as to reduce the risk of carotid vascular and neurological complications.
Key words:
Carotid body tumor; Vascular surgical procedures; Postoperative complications
Contributor Information
Zhang Wei
Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Liu Fei
Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Wang Lixin
Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Department of Vascular Surgery, Xiamen Branch, Zhongshan Hospital, Fudan University, Xiamen 361015, China
Guo Daqiao
Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Xu Xin
Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Chen Bin
Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Jiang Junhao
Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Yang Jue
Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Shi Zhenyu
Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Fu Weiguo
Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Department of Vascular Surgery, Xiamen Branch, Zhongshan Hospital, Fudan University, Xiamen 361015, China
