Original Article
CT versus MRI in TNM staging of pancreatic ductal adenocarcinoma based on the 8th AJCC
Li Bin, Lu Fengqi, Chen Fangming, Zhang Lei, Wu Wenjuan, Zhang Zhuiyang, Jin Huihan, Zhang Rongrong
Published 2020-09-28
Cite as Chin J Hepatobiliary Surg, 2020, 26(9): 661-665. DOI: 10.3760/cma.j.cn113884-20191129-00395
Abstract
ObjectiveTo compare CT with MRI on the accuracy in TNM staging of pancreatic ductal adenocarcinoma (PDAC) based on the 8th American Joint Committee on Cancer System and Pathological Staging.
MethodsFrom October 2013 to October 2019, 105 patients who had pathologically confirmed PDAC treated at the Affiliated Wuxi No.2 People’s Hospital of Nanjing Medical University were retrospectively studied. Of 52 patients who met the inclusion criteria, there were 32 males and 20 females, with age ranging from 45 to 84 years (mean 66.1 years). Based on the 8th American Joint Committee on Cancer System and Pathological Staging, CT was compared with MRI in their accuracies in categorizing TNM and staging of PDAC.
ResultsForty-three of 52 patients who underwent curative resection had a mean tumor size of (3.4±1.2) cm, compared with tumor sizes of (3.3±1.2) cm and (3.3±1.4) cm on CT and MRI, respectively. No significant differences were observed between gross pathological examination and CT (P>0.05) or MRI (P>0.05). The accuracy of T, N, and M categories on CT versus (vs) MRI was 97.7% (42/43) vs 97.7% (42/43), 79.1% (34/43) vs 76.7% (33/43), and 100% (9/9) vs 88.9% (8/9), respectively. No significant differences were observed between the two modalities (P>0.05). The overall accuracy of PDAC staging on CT vs MRI was 82.7% (43/52) vs 76.9% (40/52), respectively. There was also no significant difference between the two modalities (P>0.05).
ConclusionBoth CT and MRI had similar accuracies in categorizing TNM and staging of PDAC. However, the accuracies of T and M stages were higher than that of the N stage for these two imaging modalities.
Key words:
Pancreatic neoplasms; TNM staging; Computed tomography; Magnetic resonance imaging
Contributor Information
Li Bin
Department of Imaging, the Affiliated Wuxi No.2 People’s Hospital of Nanjing Medical University, Wuxi 214002, China
Lu Fengqi
Department of Imaging, the Affiliated Wuxi No.2 People’s Hospital of Nanjing Medical University, Wuxi 214002, China
Chen Fangming
Department of Imaging, the Affiliated Wuxi No.2 People’s Hospital of Nanjing Medical University, Wuxi 214002, China
Zhang Lei
Department of Imaging, the Affiliated Wuxi No.2 People’s Hospital of Nanjing Medical University, Wuxi 214002, China
Wu Wenjuan
Department of Imaging, the Affiliated Wuxi No.2 People’s Hospital of Nanjing Medical University, Wuxi 214002, China
Zhang Zhuiyang
Department of Imaging, the Affiliated Wuxi No.2 People’s Hospital of Nanjing Medical University, Wuxi 214002, China
Jin Huihan
Department of Hepatobiliary Surgery, the Affiliated Wuxi No.2 People’s Hospital of Nanjing Medical University, Wuxi 214002, China
Zhang Rongrong
Department of Pathology, the Affiliated Wuxi No.2 People’s Hospital of Nanjing Medical University, Wuxi 214002, China
