Clinical Research Article
Clinical characteristics of patients with septated loculations of pyogenic liver abscesses
Du Zhaoqing, Chi Miaomiao, Lin Yuxin, Wu Yunbing, Geng Xilin, Wu Rongqian
Published 2022-04-28
Cite as Chin J Hepatobiliary Surg, 2022, 28(4): 259-263. DOI: 10.3760/cma.j.cn113884-20210914-00308
Abstract
ObjectiveTo compare clinical features of patients with pyogenic liver abscesses with and without septated lobulations.
MethodsPatients diagnosed to have pyogenic liver abscesses who were treated in our hospital from January 2011 to March 2021 were enrolled into this retrospective study. There were 203 males and 132 females, with age of (56±14) years old. The patients were divided into two groups by findings on computed tomography and ultrasound into the septated lobulation group (n=68) and the non-septated lobulation group (n=267). The clinical data of these patients were compared.
ResultsIn the septated lobulation group, the neutrophil count was 9.17(5.97, 12.33)×109/L and the TBil was 17.65(11.92, 27.84) μmol/L. These were significantly higher than the corresponding figures of 7.81(5.42, 10.81)×109/L, 12.90(9.00, 19.68) μmol/L, respectively in the non-septated lobulation group (P<0.05). The difference in the maximum diameters of the septated lobulation group was also significantly larger than the non-septated lobulation group (P=0.032). Additionally, pus culture showed the proportion of Klebsiella pneumoniae positive patients in the septated lobulation group was significantly higher than that in the non-septated lobulation group [41.18% (28/68) vs. 25.84% (69/267), P=0.013]. The use of fluoroquinolones in patients in the septated lobulation group was higher than that in the non-septated lobulation group [20.59% (14/68) vs. 10.11% (27/267), χ2=5.54, P=0.019].
ConclusionCompared to patients without septated lobulations, those with septated lobulations had a larger diameter of abscesses, a higher positive rate of Klebsiella pneumoniae on pus culture and a higher proportion of patients receiving fluoroquinolones.
Key words:
Liver abscess; Klebsiella pneumonia; Septal lobulation; Percutaneous drainage
Contributor Information
Du Zhaoqing
Department of Hepatobiliary Surgery, Shaanxi Provincial People’s Hospital, Xi’an 710068, China
Chi Miaomiao
Health Science Center of Xi’an Jiaotong University, Xi’an 710061, China
Lin Yuxin
Health Science Center of Xi’an Jiaotong University, Xi’an 710061, China
Wu Yunbing
Health Science Center of Xi’an Jiaotong University, Xi’an 710061, China
Geng Xilin
Department of Hepatobiliary Surgery, Shaanxi Provincial People’s Hospital, Xi’an 710068, China
Wu Rongqian
National-Local Joint Engineering Research Center for Precision Surgery &
Regenerative Medicine, the First Affiliated Hospital, Xi’an Jiaotong University, Xi’an 710061, China
