Manling Luo, Xufei Chen, Yan Yu, Mei Zhong, Liping Wang, Jing Li, Lilin Hang, Jia Li, Wei Yin, Shiqi Yang
Abstract
ObjectiveTo explore the influencing factors affecting the success of trial of labor after cesarean (TOLAC).
MethodsDelivery outcomes of 435 pregnant women after cesarean section who had TOLAC in Nanfang Hospital of Southern Medical University between January 2009 and December 2013 were retrospectively analyzed. All of the recruited women were term singleton pregnant with cephalic presentation, spontaneous labor, history of single cesarean section (CS), but without medical problems or contraindications of vaginal delivery, and they were willing to have a trial of labor. Factors including maternal body mass index (BMI), age, interval between this delivery and last cesarean delivery, cervix dilation and effacement on admission, history of vaginal delivery, presentation of previous cesarean delivery indication, and neonatal birth weight were analyzed by bivariate analysis and multivariable logistic regression.
ResultsAmong the 435 gravidas, 315(72.4%) succeeded in vaginal birth after cesarean (VBAC), whereas 120 failed. Compared with the corresponding controls, those women whose BMI at admission <28 [75.5% (259/343) vs 60.9% (56/92)], interval between this delivery and last cesarean delivery >2 years [74.6% (256/343) vs 64.1% (59/92)] , cervix dilation >3 cm at admission [94.1% (80/85) vs 67.1%(235/350)], cervical effacement >50% at admission [82.8% (198/239) vs 59.7%(117/196)], and those who had history of vaginal birth [90.4% (103/114) vs 66.0% (212/321)], repeated indications of previous CS [74.2% (284/383) vs 59.6% (31/52)], gave birth to a baby less than 3 500 g [75.3%(223/296) vs 66.2%(92/139)] showed significantly higher VBAC successful rate [adjusted OR (95%CI): 1.982(1.220-3.221), 1.644(1.008-2.688), 7.830(3.087-19.875), 3.261( 2.098-5.069), 4.814(2.480-9.345), 1.943(1.067-3.538), 1.561(1.005-2.422), all P<0.05]. However, the VBAC success rate showed no difference between women≥35 and<35 years of age [75.0%(36/48) vs 72.1%(279/387),OR(95%CI): 0.861(0.432-1.717),P>0.05]. Multivariable logistic regression analysis showed that higher VBAC success rate was affected by vaginal delivery history [adjusted OR(95%CI): 2.927(1.553-5.517)], cervix dilation >3 cm on admission [4.146(1.549-11.100)], cervix effacement >50% on admission [2.306(1.415-3.756)].
ConclusionsThe main factors affecting the success of TOLAC are vaginal delivery history, cervix dilation and effacement on admission.
Key words:
Vaginal birth after cesarean; Delivery, obstetric; Prognosis
Contributor Information
Manling Luo
Department of Obstetrics &
Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
Xufei Chen
Department of Obstetrics &
Gynecology, Shilong People's Hospital, Dongguan 523321, China
Department of Obstetrics &
Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
Yan Yu
Department of Obstetrics &
Gynecology, Bao'an Maternal and Child Health Hospital, Shenzhen 518100, China
Department of Obstetrics &
Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
Mei Zhong
Department of Obstetrics &
Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
Liping Wang
Department of Obstetrics &
Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
Jing Li
Department of Obstetrics &
Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
Lilin Hang
Department of Obstetrics &
Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
Jia Li
Department of Obstetrics &
Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
Wei Yin
Department of Obstetrics &
Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
Shiqi Yang
Department of Obstetrics &
Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China