Review
Effect of maternal exposure to polybrominated diphenyl ethers on the development of offspring: a review
Tang Jingman, Du Lili, Chen Jingsi, Sun Wen, Chen Dunjin
Published 2020-12-16
Cite as Chin J Perinat Med, 2020, 23(12): 854-858. DOI: 10.3760/cma.j.cn113903-20200423-00373
Abstract
Pollution caused by widely used polybrominated diphenyl ethers (PBDEs) has become a global problem. PBDEs could enter the body through dietary intake, breathing and skin absorption, and can be transmitted to fetus and newborn through placenta and breastmilk. The assessment of maternal exposure level of PBDEs during pregnancy and its impact on fetal development have gained increasing attention in maternal and fetal medicine and environmental science. This article reviews the effects of maternal exposure to PBDEs on the development of offspring and its mechanisms.
Key words:
Maternal exposure; Environmental pollutants; Flame retardants; Halogenated diphenyl ethers; Fetal development
Contributor Information
Tang Jingman
Department of Obstetrics and Gynecology, the Third Affiliated Hospital of Guangzhou Medical University
Key Laboratory for Major Obstetric Diseases of Guangdong Province
Key Laboratory of Reproduction and Genetics of Guangdong Higher Education Institutes, Guangzhou 510150, China
Du Lili
Department of Obstetrics and Gynecology, the Third Affiliated Hospital of Guangzhou Medical University
Key Laboratory for Major Obstetric Diseases of Guangdong Province
Key Laboratory of Reproduction and Genetics of Guangdong Higher Education Institutes, Guangzhou 510150, China
Chen Jingsi
Department of Obstetrics and Gynecology, the Third Affiliated Hospital of Guangzhou Medical University
Key Laboratory for Major Obstetric Diseases of Guangdong Province
Key Laboratory of Reproduction and Genetics of Guangdong Higher Education Institutes, Guangzhou 510150, China
Sun Wen
Department of Obstetrics and Gynecology, the Third Affiliated Hospital of Guangzhou Medical University
Key Laboratory for Major Obstetric Diseases of Guangdong Province
Key Laboratory of Reproduction and Genetics of Guangdong Higher Education Institutes, Guangzhou 510150, China
Chen Dunjin
Department of Obstetrics and Gynecology, the Third Affiliated Hospital of Guangzhou Medical University
Key Laboratory for Major Obstetric Diseases of Guangdong Province
Key Laboratory of Reproduction and Genetics of Guangdong Higher Education Institutes, Guangzhou 510150, China