To compare the clinical efficacy of trimming apocrine glands with double small axillary fold incisions and single small incision in the radical treatment of severe axillary osmidrosis, and to clarify the histological depth of axillary apocrine glands in patients with severe axillary osmidrosis.

Fifty-four patients with severe axillary osmidrosis admitted to Beijing Shijitan Hospital Plastic Surgery Clinic from November 2016 to February 2019 were selected, among whom 27 patients underwent trimming apocrine glands with double small incisions (trial group), 27 patients underwent trimming apocrine glandswith single small incision (control group). Six patients in the trial group were randomly selected for axillary skin histopathological examination. The effective rate of postoperative treatment and the incidence of complications such as hematoma, epidermal necrosis, incision dehiscence, infection and scar were observed and analyzed statistically.

The postoperative effective rate of the trial group was 100% (27/27), significantly higher than 88.89%(24/27)of the control group (P<0.05), while the postoperative complication rate of the trial group was 11.11%(3/27), significantly lower than 33.33%(9/27) of the control group (P<0.01), and there were statistically significant differences in above two aspect comparisons. The pathological examination showed that the secretory part of apocrine glands was concentrated in the junction area between the dermis and fat and the superficial layer of adipose tissue within 0.5 cm. No apocrine gland structure was observed in the deep fat layer.

The operative method of minimally invasive radical treatment of severe axillary osmidrosis by trimming apocrine glands with double small incisions is practical and effective, and the clinical effect is significant.The depth of trimming the apocrine glands should be 0.5 cm of subcutaneous fat layer.

Minimally invasive surgical procedures; Apocrine glands; Bromhidrosis; Treatment outcome; Pathology