To investigate the clinical characteristics and risk factors of acute ischemic stroke (AIS) complicated with cerebral cardiac syndrome (CCS).

The clinical data of AIS patients admitted to the ICU of our hospital from January 2019 to May 2021 were collected and retrospectively analyzed. According to whether CCS occured after stroke, the patients were divided into the CCS group and control group. Binary logistic regression analysis was used to analyze the clinical characteristics of AIS combined with CCS and the risk factors for the occurrence of CCS.

A total of 196 patients with AIS were included, and 92 patients had CCS, of which 74 occurred within 72 h after AIS. Binary logistic regression analysis showed that old age (OR=1.15, 95%CI: 1.01-1.23), hypertension (OR=1.41, 95%CI: 1.26-1.58), diabetes (OR=2.05, 95%CI: 1.86-2.24), chronic kidney disease (OR=1.36, 95%CI: 1.22-1.48), chronic obstructive pulmonary disease (OR=1.46, 95%CI:1.22-2.48), smoking (OR=1.52, 95%CI:1.23-1.78), higher NISSH score (OR=1.36, 95%CI: 1.29-1.48), brainstem infarction (OR=2.33, 95%CI: 2.21-2.50), thalamic infarction (OR=1.21, 95%CI: 1.17-1.28), and hyperlipidemia (OR=1.86, 95%CI: 1.61-1.96) were associated with the occurrence of CCS after stroke.

CCS is a common complication in patients with AIS, and mostly occurs within 72 hours after stroke. The risk of CCS is not only related to the history of hypertension, diabetes, chronic kidney disease, smoking history and hyperlipidemia, but also related to the location of infarction and the degree of nerve function injury. The changes of cardiac function in patients with AIS should be closely monitored to prevent cardiac events.

Acute ischemic stroke; Cerebral infarction; Brain heart syndrome