Objective With the growing international exchanges and cooperation, doctors in the future need to have comprehensive medical English listening, speaking, writing and translation capabili-ties. This paper aims to find out the effective ways to help medical students to improve professional English at their clinical study phase. Methods The professional English course starts at the fourth year for medi-cal students, totaling 62 hours each year. The number of students in one class ranges from 38 to 42. The Mosby' s Crash Course, a series of tutorials in the "Pediatrics" is used as the teaching textbook. In addi-tion, some chapters of "Nelson Textbook of Pediatrics" are also adopted as the extra-reading materials. Teachers teach professional vocabulary with the help of multimedia. Special attention is given to affixes and word-building. The students are required to do role play, and extra reading material may help them en-hance English learning abilities. Results The result of survey shows that 87% of the students accept this teaching method; 92% of them claim the English class being helpful; 58% of the students think the profes-sional medical terms are difficult to master; 63% of the students believe that teaching affixation helps to ex-pand vocabulary; and 58% of the students find it easier to learn English after the adoption of the multi-media teaching methods. Conclusions To start efficient professional English course in clinical study phase is necessary for medical students. The use of multi-media teaching methods is highly recommendable and appreciated by students. By focusing on the expansion of professional vocabulary with more reading materi-als, the medical students can improve their medical English level.