Original Article
Clinical study of nasopharyngeal masses with suspicion of nasopharyngeal carcinoma in adult patients
Xiaoju Yan, Shu Fang, Guowei Huang, Jin Wang, Kailun Xu, Xinxin Zhang
Published 2018-07-07
Cite as Chin J Otorhinolaryngol Head Neck Surg, 2018, 53(7): 519-523. DOI: 10.3760/cma.j.issn.1673-0860.2018.07.007
Abstract
ObjectiveTo improve the accuracy of diagnosis and to reduce the misdiagnosis rate of nasopharyngeal carcinoma by analyzing the characteristics of such masses.
MethodsClinical data from 55 patients with suspicion of nasopharyngeal carcinoma diagnosed and treated between March 2016 and September 2017 were analyzed. All patients were followed up regularly.
ResultsWith following-up of 12 to 25 months, 6 (10.9%) of 55 cases were identified as nasopharyngeal malignant tumors, including 4 cases of nasopharyngeal carcinoma and 2 cases of lymphoma, and 49 cases (89.1%) were diagnosed with nasopharyngeal benign masses, including 29 (59.2%) cases for nasopharyngeal lymphoid proliferation, 15 (30.6%) for adenoid hypertrophy, 2 (4.1%) for nasopharyngeal cyst, 1 (2.0%) for polyp, 1 for papilloma and 1 for nasopharyngeal pharyngeal cyst. Small nasopharyngeal malignant tumor and masses with benign hyperplasia showed the overlap of images on the enhanced MRI/CT and Fibro-nasopharyngoscopy, but all 6 patients with nasopharyngeal malignant tumors presented with moderately enhanced multiple enlarged lymph nodes.
ConclusionsFibro-nasopharyngoscopy and enhanced MRI/CT have some value on evaluation of nasopharyngeal masses, but biopsy is a golden standard for diagnosis. Follow-up is necessary for the patients with negative biopsy and benign nasopharyngeal hyperplasia indicated by fibro-nasopharyngoscopy and enhanced MRI/CT.
Key words:
Nasopharyngeal neoplasms; Hyperplasia
Contributor Information
Xiaoju Yan
Department of Otorhinolaryngology Head and Neck Surgery, Guangyuan Central Hospital Affiliated to North Sichuan Medical College, Guangyuan 628000, Sichuan, China
Shu Fang
Department of Otorhinolaryngology Head and Neck Surgery, Guangyuan Central Hospital Affiliated to North Sichuan Medical College, Guangyuan 628000, Sichuan, China
Guowei Huang
Department of Otorhinolaryngology Head and Neck Surgery, PLA General Hospital, Beijing 100853, China
Jin Wang
Department of Otorhinolaryngology Head and Neck Surgery, PLA General Hospital, Beijing 100853, China
Kailun Xu
Department of Otorhinolaryngology Head and Neck Surgery, Guangyuan Central Hospital Affiliated to North Sichuan Medical College, Guangyuan 628000, Sichuan, China
Xinxin Zhang
Department of Otorhinolaryngology Head and Neck Surgery, PLA General Hospital, Beijing 100853, China
