：Objective To study theincidence of visuospatial impairment in patients with Parkinson's disease(PD)and itsrelated factors.Methods Visuospatial impairment was assessed in 107 PD patients from 6hospitals in Guangzhou during the period from April to June 2007 using cube copyingtest.The motor,neuropsyehiatric,and cognitive symptoms and the activities of dailylife(ADL)of the patients were evaluated using Hoehn-Yahr scale,Unified Parkinson's DiseaseRating Score-Ⅱ (UPDRS-Ⅱ),UPDRS-Ⅲ,UPDRS-Ⅳ,Hamilton Anxiety Scale(HAMA),Hamilton Rating Scale ofDepression(HRSD),Fuld Object-Memory Evaluation(FONt),Rapid Verbal RetrievalTest(RVR),Wechsler Adult Intelligence Scale Block Design(WISC-BD),Wechsler AdultIntelligence Scale Digid Span(WAIS-DS),Mini-Mental State Examination(MMSE),andNeuropsychiatric Inventory(NPI).Spearman correlation analysis was performed to analyze thebivariate correlation between the visual-spatial ability and the related factors,andbinary logistic regression analysis was used to identify the factors related tovisual-spatial disorder.Results Visuospatial impairment was found in 59 of the 107patients(55.14%).Logistic regression analysis identified the Hoehn-Yahr stage and durationafter disease onset as the risk factors,while RVR and WISCoBD as the protective factorsfor visuospatial impairment.Conclusion The Hoehn-Yahr stage,duration from diseaseonset,speech fluency,and image recognition and construction ability are related tovisuospatial impairment in the PD patients.The visuospatial ability of the PD patients canbe improved by relieving their motor symptoms and trainings for speech and imagerecognition and construction abilities.