Clinical Research
Interventional therapy with balloon predilation of different diameters in carotid artery stenosis: a comparative study
Chen Ruiqing, Chen Chen, Liu Zengpin
Published 2021-02-15
Cite as Chin J Neuromed, 2021, 20(2): 165-169. DOI: 10.3760/cma.j.cn115354-20200621-00498
Abstract
ObjectiveTo investigate the safety and efficacy of interventional therapy with balloon predilation of different diameters in severe carotid artery stenosis.
MethodsOne hundred patients with symptomatic severe carotid artery stenosis admitted to our hospital from January 2018 to September 2018 were selected. These patients were randomly divided into 4 mm balloon predilation group and 5 mm balloon predilation group (n=50). The surgical success rate, residual stenosis rate, changes of heart rate and blood pressure before and after surgery, and complications were compared between the two groups.
ResultsThe success rate of surgery in both groups was 100%. The average preoperative vascular stenosis rate in the 4 mm balloon predilation group was (84.8±8.6)%, and postoperative residual stenosis rate was (12.2±6.2)%, with significant difference (P<0.05); in the 5 mm balloon predilation group, the average preoperative vascular stenosis rate was (82.1±8.0)%, and the postoperative residual stenosis rate was (6.4±6.1)%, with significant difference (P<0.05). The postoperative residual stenosis rate of the 5 mm balloon predilation group was significantly lower than that of the 4 mm balloon predilation group (P<0.05). In the 4 mm balloon predilation group, systolic blood pressure decreased by (19.8±22.3) mmHg and heart rate decreased by (11.0±9.7) times/min; the systolic blood pressure decreased by (14.0±28.5) mmHg and heart rate decreased by (7.0±10.8) times/min in the 5 mm balloon predilation group; no significant differences were noted between the two groups in blood pressure and heart rate (P>0.05). Complications was noted in 28 patients from the 4 mm balloon predilation group and 25 patients from the 5 mm balloon predilation group, without statistical difference (P>0.05).
ConclusionThe application of the two kinds of diameter balloon in the interventional treatment of severe carotid artery stenosis is safe and effective, and the short-term improvement efficay of 5 mm balloon predilation is better than that of 4 mm balloon predilation.
Key words:
Carotid artery stenosis; Carotid artery stenting; Balloon predilation; Complication
Contributor Information
Chen Ruiqing
Department of Neurology, Second Hospital of Hebei Medical University, Shijiazhuang 050000, China
Chen Chen
Department of Neurology, Second Hospital of Hebei Medical University, Shijiazhuang 050000, China
Liu Zengpin
Department of Neurology, Second Hospital of Hebei Medical University, Shijiazhuang 050000, China
