Review
Recent advance in transcranial direct current stimulation in treatment of depressive disorder
Zhang Xiaoyu, Sun Xiaomeng, Fan Xu
Published 2021-10-15
Cite as Chin J Neuromed, 2021, 20(10): 1064-1069. DOI: 10.3760/cma.j.cn115354-20201109-00880
Abstract
Depression disorder is a kind of psychiatric disorders with continuously spontaneous depressive mood, characterized by depression of mood, anhedonia, sleep disturbance, decreased appetite, weight change and thoughts of death. At present, most of the patients with depression disorder are treated with antidepressant drugs, but their role in treatment are limited due to their side effects and low tolerance. Transcranial direct current stimulation (tDCS) therapy achieves satisfactory therapeutic effects as a non-invasive brain stimulation technique, at present, the clinical trials carried out widely at home and abroad have proved the advantages of tDCS: good clinical effect, being easy to tolerance, simple operation and slight side effects. This paper reviews the effect, mechanism, influencing factors, and safety of tDCS in the treatment of depression disorder, in order to provide reference for further clinical application.
Key words:
Depression disorder; Transcranial direct current stimulation; Antidepressant drug
Contributor Information
Zhang Xiaoyu
College of Acupuncture and Massage, Liaoning University of Traditional Chinese Medicine, Shenyang 110032, China
Sun Xiaomeng
College of Acupuncture and Massage, Liaoning University of Traditional Chinese Medicine, Shenyang 110032, China
Fan Xu
College of Acupuncture and Massage, Liaoning University of Traditional Chinese Medicine, Shenyang 110032, China