To analyze the epidemiological characteristics and trend of acquired immune deficiency syndrome (AIDS) in Weifang city, so as to provide scientific evidence for formulating prevention and control strategy against AIDS.

Epidemiological data of newly reported human immunodeficiency virus (HIV) infection cases and AIDS cases (HIV/AIDS) in Weifang city from 1992 to 2017 were used in descriptive analysis.

A total of 1 095 cases of HIV/AIDS were confirmed accumulately during 1992-2017. According to the number of cases of HIV/AIDS each year and growth range, there were three epidemic phases: sporadic phase (1992-2004), rapid expansion phase (2005-2011) and growth phase (2012-2017). The number of cases caused by transmission among men who have sex with men (MSM) increased from 0 case in sporadic phase to 471 cases in growth phase. The differences among demographic characteristics and transmission routes of difference epidemic phases were statistically significant (P<0.01). The average time interval from infection to testing decreased from (10.0±2.8) years in sporadic phase to (3.7±3.4) years in growth phase.

Sexual transmission was the major cause of HIV/AIDS prevalence in Weifang city. MSM was the high risk population for HIV/AIDS transmission. Optimal prevention and control measures should be developed for the high risk population.

Acquired immune deficiency syndrome; Epidemiological characteristics; Trend