Surveillance and Control of Viral Diarrhea
Epidemiological characteristics of astrovirus infection among hospitalized children with diarrhea under 5 years old in China in 2019
Wang Mingwen, Gao Shenghui, Sun Xiaoman, Li Jingxin, Li Jinsong, Li Dandi, Duan Zhaojun
Published 2022-04-25
Cite as Int J Virol, 2022, 29(2): 109-112. DOI: 10.3760/cma.j.issn.1673-4092.2022.02.005
Abstract
ObjectiveTo understand the epidemiological characteristics of astrovirus (AstV) infections among hospitalized children under 5 years old with diarrhea in China in 2019, so as to provide reference for the prevention and control of AstV diarrhea.
MethodsStool samples and clinical data of children with diarrhea were collected from the sentinel hospitals. AstV was detected by RT-PCR and the epidemiological characteristics of AstV infections were described.
ResultsA total of 4 918 stool samples were collected from hospitalized children under 5 years old with diarrhea, and 4 531 samples were tested. The detection rate of AstV was 5.30%. The lowest AstV positive rate was found in Sichuan province (1.23%), while the highest was in Gansu province (14.36%). The positive rate of AstV in male and female children was 5.14% and 4.52%, respectively, with no statistically significant difference in gender (P>0.05). There was no statistically significant differences of AstV infections in age, urban and rural areas or in seasonality (P>0.05). In AstV positive cases, the common clinical manifestations were diarrhea accompanied by vomiting. The number of diarrhea was usually 0~2 times, and the fecal character was usually watery stools.
ConclusionsAstV is one of the main causes of diarrhea in hospitalized children under 5 years old in China. The infection should be considered in clinical diagnosis and treatment. Continuous surveillance would be necessary.
Key words:
Viral diarrhea; Astrovirus; Epidemiological characteristics
Contributor Information
Wang Mingwen
National Institute for Viral Disease Control and Prevention, Chinese Center for Diseases Control and Prevention, Beijing 102206, China
Gao Shenghui
National Institute for Viral Disease Control and Prevention, Chinese Center for Diseases Control and Prevention, Beijing 102206, China
Sun Xiaoman
National Institute for Viral Disease Control and Prevention, Chinese Center for Diseases Control and Prevention, Beijing 102206, China
Li Jingxin
National Institute for Viral Disease Control and Prevention, Chinese Center for Diseases Control and Prevention, Beijing 102206, China
Li Jinsong
National Institute for Viral Disease Control and Prevention, Chinese Center for Diseases Control and Prevention, Beijing 102206, China
Li Dandi
National Institute for Viral Disease Control and Prevention, Chinese Center for Diseases Control and Prevention, Beijing 102206, China
Duan Zhaojun
National Institute for Viral Disease Control and Prevention, Chinese Center for Diseases Control and Prevention, Beijing 102206, China
