Original Article
Application of enhanced recovery after surgery concept in laparoscopic radical cystectomy and ileal conduit diversion under modular operation
Cao Zhi, Wang Kui, Hu Hanhong, Wang Wei, Yang Chenglin, Hu Zhengfei, Zhang Xiaoming, Xiao Yuansong, Wang Bangqi, Zhang Hui, Nie Haibo
Published 2021-06-15
Cite as Int J Surg, 2021, 48(6): 395-401. DOI: 10.3760/cma.j.cn115396-20210323-00109
Abstract
ObjectiveTo explore the application value of enhanced recovery after surgery (ERAS) in laparoscopic radical resection of bladder cancer and ileal bladder surgery under modular operation procedures.
MethodsA retrospective selection of 42 cases of laparoscopic radical radical resection of bladder cancer and ileal bladder surgery performed by the Department of Urology, General Hospital of Southern Theater Command from January 2017 to December 2019 were divided into two groups according to the different management methods adopted during the perioperative period: ERAS management group and conventional management group, each with 21 cases. Among them, patients in the ERAS management group were managed by ERAS during the perioperative period, and patients in the conventional management group were managed by conventional management during the perioperative period. The postoperative hospital stay, first exhaust time, first defecation time, first time to get out of bed, first liquid food time, postoperative visual analogue scale (VAS) score, as well as transferrin, upper arm circumference, body mass index, plasma albumin, total protein, and total protein were compared between the two groups of patients after surgery. The measurement data conforming to the normal distribution were expressed as mean±standard deviation (Mean±SD), and the in dependent t-test was used for comparison between groups; the measurement data of non-normal distribution were expressed as the median (interquartile range) [M(P25, P75)], the independent sample Mann-Whitney U test was used for comparison between groups; the Chi-square test was used for comparison of enumeration data between groups.
ResultsThe postoperative hospital stay in the ERAS group was (8.9±1.8) d, the first exhaust time was (33.4±3.2) h, the first defecation time was (60.3±7.8) h, the first time to get out of bed was (23.1±6.7) h, the first liquid food time was (82.7±18.5) h and postoperative VAS was (1.3±0.6), that were significantly reduced compared with the conventional treatment group [(12.3±2.3) d, (51.4±5.2) h, (73.0±8.1) h, (34.7±8.2) h, (109.7±21.6) h, (3.6±0.8)], the difference were statistically significant (P<0.05). In the ERAS group, the decreased value of transferrin was [0.8 (-0.4, 2.2) g/L], the decreased value of body mass index was[1.61±0.73], the decreased value of plasma albumin was [3.5±1.5 g/L], the decrease value of total protein was[10.1±5.6 g/L] and the decrease value of prealbumin was [90.5±11.3 mg/L] were significantly lower than those of the conventional management group[(1.9(0.9, 3.6) g/L, (2.32±1.05) kg/m2, (9.6±2.0) g/L, (16.3±4.9) g/L, (131.3±7.4) g/L], and the difference were statistically significant (P<0.05).
ConclusionModular laparoscopic precision resection of bladder cancer and ERAS concept after ileal bladder surgery is beneficial to shorten the hospital stay, reduce postoperative pain, have less impact on the patient′s body loss and immune function, and can speed up the patient′s postoperative recovery.
Key words:
Urinary bladder neoplasms; Radical cystectomy; Perioperative care; Foods for special medical purpose; Enhanced recovery after surgery
Contributor Information
Cao Zhi
Department of Urology, General Hospital of Southern Theater Command, Guangzhou 510010, China
Wang Kui
Department of Urology, General Hospital of Southern Theater Command, Guangzhou 510010, China
Hu Hanhong
Department of Urology, General Hospital of Southern Theater Command, Guangzhou 510010, China
Wang Wei
Department of Urology, General Hospital of Southern Theater Command, Guangzhou 510010, China
Yang Chenglin
Department of Urology, General Hospital of Southern Theater Command, Guangzhou 510010, China
Hu Zhengfei
Department of Urology, General Hospital of Southern Theater Command, Guangzhou 510010, China
Zhang Xiaoming
Department of Urology, General Hospital of Southern Theater Command, Guangzhou 510010, China
Xiao Yuansong
Department of Urology, General Hospital of Southern Theater Command, Guangzhou 510010, China
Wang Bangqi
Department of Urology, General Hospital of Southern Theater Command, Guangzhou 510010, China
Zhang Hui
Department of Urology, General Hospital of Southern Theater Command, Guangzhou 510010, China
Nie Haibo
Department of Urology, General Hospital of Southern Theater Command, Guangzhou 510010, China