To study the effects of Rhodiolae Crenulatae Radix ET Rhizoma extracts on sexual behavior of male mice.

50 healthy male mice were randomly divided into the low dose, middle dose and the high dose Rhodiola group, the Nanbao capsules group and the normal control group, 10 mice per group. The low dose, middle dose and high dose group were drenched with 0.05, 0.20 and 0.80 g/kg Rhodiola diluent respectively. The Nanbao capsules group mice were drenched with 2.00 g/kg turbid liquid. The normal control group were drenched with saline in the same volume. Liquid is drenched two times each day for 21 days. After 21 days, 50 female mice were matched with to the ratio of 1:1. The number of free movement and swimming test were observed before execution. After the execution, the organ indexes were calculated, and then the contents of SOD and MDA in the testis and liver were measured.

Compared with the normal control group, capturing latency period of low dose group and middle dose group (20.88±19.94 s, 35.40±22.02 s vs.78.11±43.33 s) significantly decreased (P<0.05 or P<0.01). Testicular coefficient of the middle dose group (0.72%±0.10 % vs. 0.64%±0.08%) was significantly increased (P<0.05); the content of SOD in testicular of the middle dose group, the high dose groups and the Nanbao capsules group (152.71±38.10 U/mg, 122.32±52.76 U/mg, 94.38±22.20 U/mg vs. 25.30±14.21 U/mg) increased (P<0.01); the content of SOD in liver of the middle dose group and the Nanbaocapsules group (77.71±26.35 U/mg, 74.10±26.04 U/mg vs.57.92±17.17 U/mg) significantly increased (P<0.05).

Rhodiola extract can improve the ability of sexual behavior of male mice, and improve the antioxidant capacity of testis and liver.

Radix et rhizoma rhodiolae crenumatae; Sexual behavior; Antioxidation; Mice