To explore the thoughts and rules of Ye Tianshi’s medication in the treatment of damp-resistance spleen and stomach disease in the Clinical Guideline Medical Records.

In the spleen and stomach-related diseases and dampness chapters of Clinical Guideline Medical Records, the medical cases selected in the spleen and stomach, disease syndrome ondampness were selected and entered into the Traditional Chinese Medicine Inheritance Assistance Platform System (V 2.5). The software was used to analyze the frequency, tastes, meridian, and for the association rules analysis and complex system entropy cluster analysis of medication.

A total of 162 prescriptions were included, involving 155 traditional Chinese medicines. The Poria, Magnoliae Officinalis Cortex, Citri Reticulatae Pericarpium, Atractylodis Macrocephalae Rhizoma, Alismatis Rhizoma, were used frequently. The Qi of medicationwere mainly warm, cold and flat, and the five tastes were mainly bitter, sweet and pungent, mainly belonging to the spleen, stomach and lung meridian. The core drugs in the associated network were Atractylodis Macrocephalae Rhizoma, Alismatis Rhizoma, Polyporus, Poria, Magnoliae Officinalis Cortex, Citri Reticulatae Pericarpium, Ginseng Radix et Rhizoma, Scutellariae Radix and Coptidis Rhizoma. In the analysis of the correlation between drugs, there are 106 combinations of 2 drugs, 19 combinations of 3 drugs, 1 combination of 4 drugs, and 15 drug pairs with a correlation coefficient greater than 0.03, such as " Cimicifugae Rhizoma-Puerariae Lobatae Radix" and "Atractylodis MacrocephalaeRhizoma-Cinnamomi Ramulus" , "Armeniacae Semen Amarum-Gardeniae Fructus" . Based on complex entropy clustering analysis, 5 pairs of core combinations were extracted, such as "Paeoniae Radix Alba-Coptidis Rhizoma-Nelumbinis Semen" and "Scutellariae Radix-Coptidis Rhizoma-Poria" , and 5 new prescription combinations were obtained, which had the effects of clearing heat and drying dampness, promoting Yang and surpassing dampness, regulating qi and removing dampness, warming yang and removing dampness, clearing heat and dampness.

In Clinical Guideline Medical Records, Ye Tianshi stressed regulating Qi machine, eliminating and removing discharge in the treatment of spleen and stomach diseases with dampness resistance. He often used the treatment methods of dispersing lung and removing dampness, ascending Yang and surpassing dampness, conducting Qi and guiding dampness, aromatizing dampness, warming yang and removing dampness, relieving dampness with bitterness, reducing dampness, clearing heat and removing dampness.

Spleen system diseases; Clinical Guideline Medical Records; Ye Tianshi; Wet syndrome; Data mining