To observe and analyze the effectiveness of programmed analgesia and sedation in ICU on reduction of the incidence of ventilator-associated pneumonia (VAP).

Forty-five tracheal intubation patients admitted in ICU of the People's Hospital of Lujiang County from June 2018 to May 2019 were selected as the observation group.Infection Control Office organized a conference on ICU quality control in the ICU department to train the latest 2018 Chinese Adult ICU Analgesia and Sedation Treatment Guidelines, formulated and implemented a program-oriented analgesia and sedation process with shallow sedation as the goal, which stipulated that doctors develop analgesia and sedation plans and goals, nurses dynamically assess the patients' analgesia and sedation target and adjust drugs based on the evaluation results, and Infection Control Office supervised the implement of process.Forty-five patients with tracheal intubation treatment from January 2018 to May 2018 were included in the conventional group.Drug sedation and analgesia were used in accordance with traditional methods, and drug dose adjustment was performed according to doctor's orders.The time of mechanical ventilation, the incidence of VAP, and the time of ICU stay were compared between the two groups.

The incidence of VAP in the observation group was 11.11%(5/45), which in the conventional group was 31.11%(14/45), and the difference was statistically significant between the two groups(χ²=4.27, P<0.05). The mechanical ventilation time [(55.85±53.37)h] and the time of ICU stay [(62.65±58.73)h] of the observation group were slightly shorter than those of the conventional group [(60.06±31.07)h, (64.61±33.84)h], but the differences were not statistically significant(allP>0.05).

Programmed analgesia and sedation can effectively reduce the incidence of VAP in patients with mechanical ventilation.

Pneumonia, ventilator-associated; Respiration, artificial; Deep sedation; Analgesia