Field Epidemiological Investigation
Investigation on an epidemic of serogroup W135 Neisseria meningitidis infections in Hangzhou
Zhang Xuechao, Che Xinren, Zhang Xiaoping, Xu Yuyang, Zheng Wei, Xi Ying, Du Jian, Wang Jun, Gu Wenwen, Liu Yan
Published 2021-02-25
Cite as Inter J Epidemiol Infect Dis, 2021, 48(1): 55-58. DOI: 10.3760/cma.j.cn331340-20200701-00216
Abstract
ObjectiveTo investigate an epidemic of serogroup W135 Neisseria meningitidis infections in a spa center, so as to provide references for effective disposals of the disease.
MethodsA field epidemiological method was conducted to investigate 1 patient with W135 invasive meningococcal infection and 105 close contacts in a spa center in Hangzhou, and throat swab specimens were collected for pathogen isolation and identification.
ResultsAccording to the results of epidemiological investigation, clinical symptoms and laboratory test, this patient was confirmed as a W135 meningococcal case. A total of 9 isolates of Neisseria meningitidis were identified from the throat swab specimens of 103 close contacts who accepted sampling, with positive rate of 8.74%. Additionally, 1 case was identified as serogroup B infection and no other cases were confirmed subsequently.
ConclusionsThis is the first W135 invasive meningococcal case detected in Hangzhou. Neisseria meningitidis serogroup B is isolated from the close contacts, which warns that the epidemic strain of cerebrospinal meningitis in this area has changed.
Key words:
Neisseria meningitidis; Meningococcal meningitis; Serogroup W135; Epidemiological investigation; Close contact
Contributor Information
Zhang Xuechao
Department of Immunization, Hangzhou Municipal Center for Disease Control and Prevention, Hangzhou 310021, China
Che Xinren
Department of Immunization, Hangzhou Municipal Center for Disease Control and Prevention, Hangzhou 310021, China
Zhang Xiaoping
Department of Immunization, Hangzhou Municipal Center for Disease Control and Prevention, Hangzhou 310021, China
Xu Yuyang
Department of Immunization, Hangzhou Municipal Center for Disease Control and Prevention, Hangzhou 310021, China
Zheng Wei
Department of Microbiology Laboratory, Hangzhou Municipal Center for Disease Control and Prevention, Hangzhou 310021, China
Xi Ying
Department of Infectious Disease Prevention and Control, Jianggan District Center for Disease Control and Prevention, Hangzhou 310004, China
Du Jian
Department of Immunization, Hangzhou Municipal Center for Disease Control and Prevention, Hangzhou 310021, China
Wang Jun
Department of Immunization, Hangzhou Municipal Center for Disease Control and Prevention, Hangzhou 310021, China
Gu Wenwen
Department of Immunization, Hangzhou Municipal Center for Disease Control and Prevention, Hangzhou 310021, China
Liu Yan
Department of Immunization, Hangzhou Municipal Center for Disease Control and Prevention, Hangzhou 310021, China
