Clinical Medicine
Descriptive epidemiological study of hyperkalemia among patients in the emergency department
Bian Jiaming, Han Haijian, Yu Xuezhong, Zuo Li, Zhao Houyu, Han Xu
Published 2021-03-10
Cite as Chin J Emerg Med, 2021, 30(3): 312-317. DOI: 10.3760/cma.j.issn.1671-0282.2021.03.010
Abstract
ObjectiveTo describe the incidence, diagnosis rate, treatment rate and treatment pattern of hyperkalemia, and serum potassium retesting rate among hyperkalemia patients in the emergency department.
MethodsData were derived from Military Data Center for Rational Use of Drugs. Patients who accessed emergency medical services (≥18 years old) with record(s) of serum potassium between 2015 and 2017 were included. The data of laboratory test, diagnosis, and treatment were analyzed. The main outcomes included the incidence of hyperkalemia, the diagnosis rate, the treatment rate, treatment pattern and the 7-day retesting rate.
ResultsA total of 1 039 245 patients who met the above criteria were included, of whom, 36 615 (3.52%) had at least one hyperkalemia event. Among the emergency patients with chronic kidney disease, heart failure, diabetes mellitus and hypertension, the proportions of patients who experienced hyperkalemia were 47.69%, 29.13%, 21.69% and 10.16%, respectively. The diagnosis rate of emergency hyperkalemia patients was 9.23%. The overall hyperkalemia treatment rate was 42.1%. Insulin + glucose injection was the most commonly used therapy for emergency hyperkalemia patients. The overall serum potassium retesting rate within 7 days was 28.8%.
ConclusionsHyperkaliemia is more common and more severe in patients with chronic kidney disease, heart failure, diabetes and hypertension. The diagnosis rate and retesting rate of hyperkalemia are low, suggesting that the identification and management of hyperkaliemia in emergency patients should be strengthened.
Key words:
Hyperkalemia; Disease distribution; Epidemiology; Emergency department
Contributor Information
Bian Jiaming
Department of Pharmacology, the 7th Medical Center of Chinese PLA General Hospital, Beijing 100700, China
Han Haijian
Medical Service Center of Chinese PLA General Hospital, Beijing 100853, China
Yu Xuezhong
Department of Emergency, Chinese Academy of Medical Sciences &
Peking Union Medical College Hospital, Beijing 100730, China
Zuo Li
Department of Nephrology, Peking University People's Hospital, Beijing 100044, China
Zhao Houyu
Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China
Han Xu
Department of Pharmacology, the 7th Medical Center of Chinese PLA General Hospital, Beijing 100700, China