Experimental and Prescriptions of Chinese Medicine
Quality evaluation of Astmgali radix based on multivariate statistical analysis
Zhai Yuyao, Duan Wanli, Hu Mingxun, Guo Baolin
Published 2022-04-30
Cite as Int J Trad Chin Med, 2022, 44(4): 416-421. DOI: 10.3760/cma.j.cn115398-20210204-00035
Abstract
ObjectiveTo explore the feasibility of using multivariate statistical analysis to evaluate the quality of Astmgali radix from different habitats.
MethodsThe contents of Astragaloside saponinⅠ, Astragalus saponin Ⅱ, Astragaloside Ⅲ and Astragaloside A were determined by UPLC-ELSD. The components of astragalus saponins from different habitats were analyzed by TOPSIS and cluster thermogram.
ResultsTOPSIS analysis showed that the comprehensive quality of Astmgali radix samples from Shanxi, Gansu and Inner Mongolia was related(were 0.297 3, 0.346 0, 0.322 5), and the whole quality of S13 and S14 from Shanxi and N5 from Inner Mongolia were higher than others. Cluster thermogram showed that Astmgali radix was grouped into three groups according to region, and the quality difference of Astmgali radix was mainly reflected on Astragaloside saponinⅠand Astragalus saponin Ⅱ.
ConclusionsThe theory of multivariate statistical analysis is perfect, objective and reliable. It can be used as a reference for comprehensive quality evaluation of Traditional Chinese Medicine (TCM), selection of excellent germplasm resources and traceability of origin of TCM.
Key words:
Astmgali radix (TCD); Multivariate statistical analysis; Quality control
Contributor Information
Zhai Yuyao
Department of Pharmacy, Xi'an People's Hospital (Xi'an Fourth Hospital), Xi'an 710004, China
Duan Wanli
Department of Urology, Shaanxi Provincial People's Hospital, Xi'an 710068, China
Hu Mingxun
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China
Guo Baolin
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China