Radiological Hygiene
Risk estimation for lung cancer caused by indoor radon exposure in China based on EPA/BEIR-VI model
Miao Xiaoxiang, Su Yinping, Zhuo Weihai, Sun Quanfu
Published 2022-01-25
Cite as Chin J Radiol Med Prot, 2022, 42(1): 45-49. DOI: 10.3760/cma.j.cn112271-20210822-00338
Abstract
ObjectiveTo estimate the attribution share of residents′lung cancer caused by indoor Radon.
MethodsBased on the 2015 lung cancer mortality, all-cause mortality from China together with nationally representative smoking rate and the average indoor radon concentration of 30 Bq/m3, the relatively authoritative and applicable EPA/BEIR-VI risk model was used to predict the lung cancer mortality caused by indoor radon exposure.
ResultsThe excess relative risk (ERR) of indoor radon-related lung cancer mortality among the male non-smokers is higher than that of smokers. For the age-group above 50, the male smokers and male non-smokers have the highest ERR values, which were 0.511 and 0.230, respectively. Assuming the exposure incurred starting at age 0 with the same radon concentration, the lifetime risk of men and women non-smokers is higher than that of the smokers of the same gender. The higher the radon concentration, the higher the lifetime risk of lung cancer. Assuming that the radon concentration level in China is 30 Bq/m3, the number of deaths from indoor radon-related lung cancer in 2015 is about 55 512. According to this, about 6.62% of lung cancers are caused by indoor radon exposure. If we assume that radon concentration levels are 40 Bq/m3and 70 Bq/m3 in China, approximately 8.82% and 15.38% of lung cancer deaths can be attributed to indoor radon exposure.
ConclusionsIndoor radon exposure is an important environmental factor that causes Chinese residential lung cancer. Effective measures should be taken to prevent and control the increasing indoor radon levels. In order to accurately assess risk of lung cancer morality caused by indoor radon, more detailed data such as the indoor radon level in China are needed.
Key words:
EPA/BEIR-VI model; Indoor Radon; Radon exposure; Risk of Lung cancer
Contributor Information
Miao Xiaoxiang
Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China
Su Yinping
Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China
Zhuo Weihai
Institute of Radiation Medicine, Fudan University, Shanghai 310000, China
Sun Quanfu
Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China
