Short Original Article
Sensitization characteristics of Juniperus chinensis pollen in Beijing area
Ma Tingting, He Ning, Wang Hongtian, Chen Yanlei, Zhuang Yan, Shi Haiyun, Lan Tianfei, Guo Miaoying, Yu Ruili, Wang Ye, Wang Xueyan
Published 2022-04-07
Cite as Chin J Otorhinolaryngol Head Neck Surg, 2022, 57(4): 479-484. DOI: 10.3760/cma.j.cn115330-20210701-00416
Abstract
ObjectiveTo investigate the sensitization characteristics of Juniperus chinensis pollen in patients with allergic rhinitis and/or allergic asthma in Beijing area, and to explore the characteristics of Juniper chinensis pollen sensitized population.
MethodsPatients with suspected allergic rhinitis and/or asthma from January 2017 to December 2019 in the outpatient department of Allergy Department of Beijing Shijitan Hospital were selected in this study. Skin prick test (SPT) was performed with Juniper chinensis pollen allergen reagent to compare different age and disease allergen distribution, and to observe the sensitization characteristics of its population. All of the analyses were performed using SAS software version 9.4.
ResultsA total of 8 380 patients were enrolled in the end. The total positive rate of Juniper chinensis pollen SPT reached 49.92% (4 183/8 380). The positive rate of Juniper chinensis pollen SPT was highest in the 10-14 age group, reaching 60.99% (283/464). Compared with other age groups, there was a statistical difference (χ²=266.77, P<0.01). The SPT positive rate of patients aged less than 10 years increased with the increase of age, while the SPT positive rate of patients aged over 40 years decreased with the increase of age. Single Juniper chinensis pollen was less allergenic, accounting for about 25.05% (1 048/4 183), and the patients′ age was (35.21±12.39) years. Regardless of single Juniper chinensis pollen or other pollen allergies, allergic rhinitis was the main disease. Among the patients with SPT positive Juniper chinensis pollen combined with other inhaled pollen allergens, willow pollen accounted for the first (74.99%). The positive rate of Juniper chinensis pollen was the highest in patients with single allergic rhinitis, accounting for 52.05% (3 797/7 295), and the rate in patients with single allergic asthma was the lowest, accounting for 17.49% (53/303), with statistically difference (χ²=138.99, P<0.01).
ConclusionsJuniper chinensis pollen is highly sensitized in patients with allergic rhinitis and/or allergic asthma in Beijing . The positive rate of SPT is highest among 10-14 age group, most of which showed strong positive reaction, and allergic rhinitis is more common in Juniper chinensis pollen sensitization diseases.
Key words:
Skin prick test; Allergic rhinitis; Allergic asthma; Juniperus chinensis; Pollen
Contributor Information
Ma Tingting
Department of Allergy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
He Ning
Department of Allergy, Yantai Yuhuangding Hospital of Qingdao University, Yantai 264000, China
Wang Hongtian
Department of Allergy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
Chen Yanlei
Department of Allergy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
Zhuang Yan
Department of Allergy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
Shi Haiyun
Department of Allergy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
Lan Tianfei
Department of Allergy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
Guo Miaoying
Department of Allergy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
Yu Ruili
Department of Allergy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
Wang Ye
School of Population Medicine and Public Health, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China
Wang Xueyan
Department of Allergy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
