Field Epidemiological Investigation
Analysis of monitoring results of skeletal fluorosis in coal-burning type endemic fluorosis areas in Guizhou Province
Gao Jing, Li Yang, Xiang Hong, Ye Hongbing, Zhang Boyou, Wang Xiaoming, Yao Dancheng
Published 2023-11-20
Cite as Chin J Endemiol, 2023, 42(11): 888-892. DOI: 10.3760/cma.j.cn231583-20220902-00304
Abstract
ObjectiveTo analyze the monitoring results of skeletal fluorosis in coal-burning type endemic fluorosis areas in Guizhou Province, and evaluate the effectiveness of comprehensive treatment of coal-burning type endemic fluorosis in the affected areas.
MethodsIn 2009, 2014, and 2019, monitoring of skeletal fluorosis was carried out in six counties (cities, districts) of Renhuai City, Qixingguan District, Dafang County, Qianxi City, Puding County, and Pu'an County in Guizhou Province. Age stratification was conducted in each county (city, district) for permanent residents aged 25 and above, and survey subjects were selected for X-ray examination of skeletal fluorosis.
ResultsThe detection rates of skeletal fluorosis in 2009, 2014, and 2019 were 51.48% (798/1 550), 34.88% (308/883), and 6.51% (60/922), respectively, showing a decreasing trend year by year (χ2trend = 505.83, P < 0.001), decreased by 44.97 percentage points from 2009 to 2019. The age distribution of patients with skeletal fluorosis was mainly in the age group of 55 years and older, with annual proportions of 53.88% (430/798), 56.49% (174/308), and 78.33% (47/60), all higher than 50%. In 2009, 2014, and 2019, 483, 222 and 21 cases of mild skeletal fluorosis were detected, and 315, 86, and 39 cases of moderate to severe skeletal fluorosis were detected. There was a statistically significant difference in disease grading among different years(χ2 = 32.63, P < 0.001). Among them, there were statistically significant differences in the grading of skeletal fluorosis in Qixingguan District, Qianxi City, Puding County, and Pu'an County(χ2 = 14.56, 12.24, 35.01, 23.35, P < 0.05).
ConclusionsThe detection rate of skeletal fluorosis in Guizhou Province decreases year by year, and the prevention and control effect is significant. Patients with skeletal fluorosis are mainly in the age group of 55 years and older, and the proportion of patients with moderate to severe skeletal fluorosis is increasing. We should continue to monitor and manage the treatment of current patients with skeletal fluorosis.
Key words:
Fluoride; Coal; Skeletal fluorosis; Monitoring
Contributor Information
Gao Jing
Department of Epidemiology, Institute of Endemic Disease, Guizhou Center for Disease Control and Prevention, Guiyang 550004, China
Li Yang
Department of Epidemiology, Institute of Endemic Disease, Guizhou Center for Disease Control and Prevention, Guiyang 550004, China
Xiang Hong
Department of Epidemiology, Institute of Endemic Disease, Guizhou Center for Disease Control and Prevention, Guiyang 550004, China
Ye Hongbing
Department of Epidemiology, Institute of Endemic Disease, Guizhou Center for Disease Control and Prevention, Guiyang 550004, China
Zhang Boyou
Department of Epidemiology, Institute of Endemic Disease, Guizhou Center for Disease Control and Prevention, Guiyang 550004, China
Wang Xiaoming
Department of Epidemiology, Institute of Endemic Disease, Guizhou Center for Disease Control and Prevention, Guiyang 550004, China
Yao Dancheng
Department of Epidemiology, Institute of Endemic Disease, Guizhou Center for Disease Control and Prevention, Guiyang 550004, China
