Original Article
Application of the Chinese version of the Morisky Medication Adherence Scale-8 in the treatment of Kashin-Beck disease reliability and validity analysis
Niu Hui, Yang Zhengjun, Chang Hong, Deng Xingxing, Wen Jinfeng, Zhao Yijun, Zhang Qian, Li Wenyu, Zhang Feng, Guo Xiong, Wu Cuiyan
Published 2024-04-20
Cite as Chin J Endemiol, 2024, 43(4): 263-268. DOI: 10.3760/cma.j.cn231583-20230531-00130
Abstract
ObjectiveTo evaluate the reliability and validity of Chinese version of the Morisky Medication Adherence Scale-8 (MMAS-8) in drug therapy for Kashin-Beck disease (KBD), and to explore the influencing factors on medication adherence of patients with KBD.
MethodsIn September 2022, a total of 120 patients with KBD in Yaozhou District of Tongchuan City, Shaanxi Province were investigated medication adherence using the Chinese version of MMAS-8, and the general information of patients such as gender, age, height, weight, KBD degree, smoking, drinking, education level, and chronic diseases were collected. Pearson correlation coefficient was used to analyze the correlation between each item score and the total score. Test-retest reliability, split-half reliability coefficient and Cronbach's α coefficient were used to evaluate the reliability of the Chinese version of MMAS-8. Principal component factor analysis was used to evaluate the construct validity. Multivariate ordinal logistic analysis was used to analyze the influencing factors of medication adherence in patients with KBD.
ResultsAmong the 120 patients, 70 patients (58.3%) showed low medication adherence, 41 patients (34.2%) showed moderate medication adherence, and 9 patients (7.5%) showed high medication adherence. The Person correlation coefficient between each item score and the total score of the Chinese version of MMAS-8 were all greater than 0.40. The test-retest reliability was 0.78, the split-half reliability coefficient was 0.66, and the Cronbach's α coefficient was 0.72. Principal component factor analysis extracted two common factors, and the cumulative variance contribution rate was 52.30%. Multivariate ordinal logistic analysis showed that patients with drinking habits had lower medication adherence than those without drinking habits (OR = 0.25, 95%CI: 0.07 - 0.83, P = 0.024), meanwhile, the other factors were not statistically significant (P > 0.05).
ConclusionsThe application of the Chinese version of MMAS-8 in the treatment of patients with KBD has good reliability and validity. Drinking habits are related to medication adherence in patients with KBD.
Key words:
Kashin-Beck disease; Chinese version of the Morisky Medication Adherence Scale-8; Reliability and validity analysis; Influencing factor
Contributor Information
Niu Hui
Key Laboratory of Trace Elements and Endemic Diseases of National Health Commission, School of Public Health, Xi'an Jiaotong University, Xi'an 710061, China
Yang Zhengjun
Department of Kashin-Beck Disease and Keshan Disease, Shaanxi Institute for Endemic Disease Control and Research, Xi'an 710003, China
Chang Hong
Department of Kashin-Beck Disease and Keshan Disease, Shaanxi Institute for Endemic Disease Control and Research, Xi'an 710003, China
Deng Xingxing
Key Laboratory of Trace Elements and Endemic Diseases of National Health Commission, School of Public Health, Xi'an Jiaotong University, Xi'an 710061, China
Wen Jinfeng
Key Laboratory of Trace Elements and Endemic Diseases of National Health Commission, School of Public Health, Xi'an Jiaotong University, Xi'an 710061, China
Zhao Yijun
Key Laboratory of Trace Elements and Endemic Diseases of National Health Commission, School of Public Health, Xi'an Jiaotong University, Xi'an 710061, China
Zhang Qian
Key Laboratory of Trace Elements and Endemic Diseases of National Health Commission, School of Public Health, Xi'an Jiaotong University, Xi'an 710061, China
Li Wenyu
Key Laboratory of Trace Elements and Endemic Diseases of National Health Commission, School of Public Health, Xi'an Jiaotong University, Xi'an 710061, China
Zhang Feng
Key Laboratory of Trace Elements and Endemic Diseases of National Health Commission, School of Public Health, Xi'an Jiaotong University, Xi'an 710061, China
Guo Xiong
Key Laboratory of Trace Elements and Endemic Diseases of National Health Commission, School of Public Health, Xi'an Jiaotong University, Xi'an 710061, China
Shaanxi Endemic Diseases Clinical Medical Research Center, Xi'an 710004, China
Wu Cuiyan
Key Laboratory of Trace Elements and Endemic Diseases of National Health Commission, School of Public Health, Xi'an Jiaotong University, Xi'an 710061, China
Shaanxi Endemic Diseases Clinical Medical Research Center, Xi'an 710004, China
