To analyze distribution of pathogenic bacteria, drug resistance of main pathogenic bacteria and infection markers in urinary system infection, so as to provide experimental basis for the diagnosis and treatment of urinary system infection.

The common pathogens and drug resistance of 2 620 patients with urinary system infection treated in 940th Hospital of Joint Logistic Support Force from January 2017 to January 2020 were analyzed. Clinical infection biomarkers of urinary sediment white blood cells (WBC), urinary sediment red blood cells (RBC), serum procalcitonin (PCT), serum interleukin-6(IL-6) and blood routine neutrophil percentage (NEU), the receiver operator characteristic(ROC) curve was analyzed and 846 patients without infection were randomly selected as negative control.

The urinary tract infection accounted for 5.39% (64/1 186) of bloodstream infection patients. The first pathogenic bacteria of urinary tract infection was Escherichia coli 40.08% (1 050/2 620), followed by Enterococcus faecium 13.89% (364/2 620) and Enterococcus faecalis 6.64% (174/2 620). The lower resistance rate of Escherichia coli was amoxicillin/clavulanic acid, piperacillin/tazobactam, imipenem, ertapenem, amikacin, tobramycin and furantoin, the resistance rates were 10.9%, 2.0%, 1.4%, 0, 2.4% and 5.6% respectively. The area AUC under the ROC curve of urine sediment WBC was 0.861 for uncomplicated urinary tract infection, and the sensitivity and specificity were 0.865 and 0.810 for urinary routine WBC≥10.2 /μL, respectively.

The pathogenic bacteria of urinary system infection are complex, the incidence of bloodstream infection is low, and the drug resistance rate of common pathogenic bacteria Escherichia coli is low. Clinicians can guide the rational use of antibiotics according to the epidemiological experience and the results of midstream urine culture drug sensitivity test. The infection biomarkers is only urinary sediment WBC, which has high clinical diagnostic value for urinary system infection.

Urinary Tract Infections; Escherichia Coli; Leukocytes; Erythrocytes