Viral Hepatitis
Epidemiological analysis of the current prevalence of hepatitis B virus infection among pregnant and postpartum women in China from 2021 to 2023
Huang Dongxu, Wang Xiaoyan, Wang Qian, Gao Ya, Wang Yu, Wang Changhe, Wang Ailing
Published 2024-05-20
Cite as Chin J Hepatol, 2024, 32(5): 449-452. DOI: 10.3760/cma.j.cn501113-20240422-00219
Abstract
ObjectiveTo analyze hepatitis B serologic tests and the current prevalence of hepatitis B virus (HBV) infection among pregnant and postpartum women in China from 2021 to 2023.
MethodsData on managing the prevention of mother-to-child transmission of HIV, syphilis, and hepatitis were retrieved from the National Information System. A positive serum HBsAg test was used to define HBV infection. The χ2 test was used to compare the coverage rate of the hepatitis B serologic test across different years, in early-stage pregnancy, and the current HBV infection in pregnant and postpartum women. A two-sided P value of <0.05 was considered a statistically significant difference.
ResultsThe coverage rate for hepatitis B serological detection in pregnant (including intrapartum) and postpartum women and early-stage pregnancy rose from 99.68% (10 463 059/10 496 883) and 82.96% (8 707 765/10 496 883) to 99.94% (8 678 777/8 684 387, P < 0.001) and 88.87% (7 717 857/8 684 387, P < 0.001) in China between 2021 and 2023. The current prevalence rate of HBV infection decreased from 4.98% (521 479/10 463 059) in 2021 to 4.56% (396 148/8 678 777) in 2023 among pregnant and postpartum women (P < 0.001). The current prevalence rate of HBV infection ranged from 1.53% to 10.39% among pregnant and postpartum women in various provinces of China in 2023.
ConclusionThe coverage rate for hepatitis B serologic tests in China increased significantly between 2021 and 2023 in pregnant and postpartum women. Therefore, the current prevalence rate of HBV infection has decreased significantly in pregnant and postpartum women, but a regional difference still exists.
Key words:
Gravida; Parturient; Hepatitis B; Hepatitis B virus; Infection; Epidemiology; Serology
Contributor Information
Huang Dongxu
National Center for Women and Children's Health, Chinese Center for Disease Control and Prevention, Beijing 100081, China
Wang Xiaoyan
National Center for Women and Children's Health, Chinese Center for Disease Control and Prevention, Beijing 100081, China
Wang Qian
National Center for Women and Children's Health, Chinese Center for Disease Control and Prevention, Beijing 100081, China
Gao Ya
National Center for Women and Children's Health, Chinese Center for Disease Control and Prevention, Beijing 100081, China
Wang Yu
National Center for Women and Children's Health, Chinese Center for Disease Control and Prevention, Beijing 100081, China
Wang Changhe
National Center for Women and Children's Health, Chinese Center for Disease Control and Prevention, Beijing 100081, China
Wang Ailing
National Center for Women and Children's Health, Chinese Center for Disease Control and Prevention, Beijing 100081, China
