Review
Research progress on the effects of exposure to major persistent organic pollutants during pregnancy on the functional development of nervous system in children
Wu Shuqi, Liu Borui, Yang Zhe, Zheng Lu, Wang Xiaochuan, Yang Xinyue, Jia Lihong, Hu Jiajin
Published 2024-06-06
Cite as Chin J Prev Med, 2024, 58(6): 917-923. DOI: 10.3760/cma.j.cn112150-20231028-00299
Abstract
Persistent Organic Pollutants (POPs) have the characteristics of resistance to environmental degradation, bioaccumulation and long-distance migration potential. Maternal exposure to POPs during pregnancy can enter the fetal blood circulation through the placental barrier, and have a potential impact on the functional development of the nervous system of the offspring. This in turn leads to the occurrence and development of neurological defects and diseases in adulthood. The purpose of this paper is to elucidate the effects of exposure to three major POPs (organochlorine compounds, perfluoroalkyl and polyfluoroalkyl substances, and polybrominated diphenyl ethers) during pregnancy on the functional development of the nervous system (social emotions, cognition, language, exercise, and adaptability) in children, and to provide reference for subsequent studies.
Key words:
Persistent organic pollutants; Nervous system function; Child development; Intrauterine exposure; Review
Contributor Information
Wu Shuqi
Key Laboratory of Obesity and Glucose, Lipid Associated Metabolic Diseases of Liaoning Province/Health Sciences Institute, China Medical University, Shenyang 110122, China
Liu Borui
Key Laboratory of Obesity and Glucose, Lipid Associated Metabolic Diseases of Liaoning Province/Health Sciences Institute, China Medical University, Shenyang 110122, China
Yang Zhe
Key Laboratory of Obesity and Glucose, Lipid Associated Metabolic Diseases of Liaoning Province/Health Sciences Institute, China Medical University, Shenyang 110122, China
Zheng Lu
Key Laboratory of Obesity and Glucose, Lipid Associated Metabolic Diseases of Liaoning Province/Health Sciences Institute, China Medical University, Shenyang 110122, China
Wang Xiaochuan
Key Laboratory of Obesity and Glucose, Lipid Associated Metabolic Diseases of Liaoning Province/Health Sciences Institute, China Medical University, Shenyang 110122, China
Yang Xinyue
Key Laboratory of Obesity and Glucose, Lipid Associated Metabolic Diseases of Liaoning Province/Health Sciences Institute, China Medical University, Shenyang 110122, China
Jia Lihong
School of Public Health, China Medical University, Shenyang 110122, China
Hu Jiajin
Key Laboratory of Obesity and Glucose, Lipid Associated Metabolic Diseases of Liaoning Province/Health Sciences Institute, China Medical University, Shenyang 110122, China
