Infection and Prevention of Human Respiratory Syncytial Virus
Epidemiological characteristics of human respiratory syncytial virus in influenza-like illness in Shenzhen City from 2019 to 2023
Ying Sun, Weihua Wu, Yalan Huang, Shisong Fang, Hui Liu, Min Jiang, Jun Meng, Xuan Zou, Xin Wang
Published 2024-08-06
Cite as Chin J Prev Med, 2024, 58(8): 1117-1123. DOI: 10.3760/cma.j.cn112150-20240318-00223
Abstract
ObjectiveTo understand the epidemiological characteristics of human respiratory syncytial virus (HRSV) among cases presenting with influenza-like illness (ILI) in Shenzhen City from 2019 to 2023.
MethodsRespiratory specimens were collected from two national sentinel hospitals in Shenzhen from March 2019 to December 2023, specifically targeting cases of ILI. The real-time PCR method was used for the detection and genotyping of HRSV. Basic demographic information was collected and used for the epidemiological analysis.
ResultsA total of 9 278 respiratory specimens of influenza-like cases were collected and detected, with a total positive rate of 4.77% (443/9 278) for HRSV. In 2021 (8.48%, 167/1 970), the positive rate of HRSV was significantly higher than in 2019 (3.35%, 52/1 552), 2022 (1.80%, 39/2 169), and 2023 (4.49%, 133/2 960), and the difference was statistically significant (χ2=102.395, P<0.001). The prevalence of HRSV was mainly in summer and early autumn (September), and there was an abnormal increase in the positive rate of HRSV in winter 2022. The highest positive rate of HRSV was in children under five years old (9.84%, 330/335). The typing results showed that in 2022, the prevalence of HRSV-A was predominant (71.79%, 28/39), and in 2023, HRSV-A and HRSV-B subtypes coexisted.
ConclusionsThe prevalence of HRSV in Shenzhen from 2019 to 2023 has obvious seasonality, mainly in summer and early autumn. Children under five years old are the main population of HRSV infections.
Key words:
Shenzhen city; Human respiratory syncytial virus; Influenza-like illness; Epidemiological characteristics
Contributor Information
Ying Sun
Department of Pathogen Detection, Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China
Weihua Wu
Department of Pathogen Detection, Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China
Yalan Huang
Department of Pathogen Detection, Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China
Shisong Fang
Department of Pathogen Detection, Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China
Hui Liu
Department of Pathogen Detection, Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China
Min Jiang
Department of Pathogen Detection, Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China
Jun Meng
Department of Pathogen Detection, Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China
Xuan Zou
Department of Pathogen Detection, Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China
Xin Wang
Department of Pathogen Detection, Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China
