Original Article
Analysis of viral infections in adult acute respiratory infection cases in Shanghai, 2023
Wang Huanru, Mou Jiabin, Qiu Qi, Liu Jiajing, Yuan Fang, Liu Meihua, Tang Xiaode, Zhang Jingyi, Chen Jian, Chen Min, Wu Huanyu, Teng Zheng
Published 2024-08-30
Cite as Chinese J Exp Clin Virol, 2024, 38(4): 439-445. DOI: 10.3760/cma.j.cn112866-20240409-00058
Abstract
ObjectiveTo elucidate the etiological and epidemiological characteristics and epidemiological patterns of viral acute respiratory infections (ARI) in Shanghai during 2023, with the aim of providing robust laboratory evidence for effective prevention and control strategies against related respiratory diseases and facilitating risk assessment.
MethodsRespiratory pathogens were detected in the clinical surveillance specimens submitted by sentinel hospitals through multiplex PCR, as part of the multi-pathogen surveillance of acute respiratory infections in Shanghai during 2023. The obtained detection result were statistically analyzed in conjunction with sample information.
ResultsThe positive detection rate of viral pathogens in 2023 was 21.17% (984/4 648), with rates of 33.53% (504/1 503) observed in ILI cases and 15.62% (480/3 145) in SARI cases. Influenza A virus (FluA) was the predominant virus detected, accounting for 13.7% (637/4 648). Other viruses identified in the surveillance samples included influenza B virus (Flu B), human rhinovirus/enterovirus (HRV/HEV), respiratory syncytial virus (RSV), human metapneumovirus (HMPV), parainfluenza virus (PIV), adenovirus (ADV) and human bocavirus (HBoV). Regarding temporal distribution, HRV/HEV and RSV exhibited the highest detection rates during the second quarter at 2.27% each (28/1 236). PIV had its peak during the third quarter at a rate of 2.49% (35/1 405), and HMPV showed prevalence mainly during the third and fourth quarters, with detection rates of 2.63% (37/1 405) and 2.35% (32/1 360), respectively.
ConclusionsIn acute respiratory infection surveillance cases in Shanghai in 2023, Flu A emerged as the predominant respiratory pathogen. The detection rate of HMPV ranked second only to Flu A, while other respiratory viruses such as HRV/HEV, RSV, and PIV were detected during different seasons and co-circulated. The prevalence of various respiratory viruses varied among different infected populations and over times.
Key words:
Acute respiratory infection; Respiratory viruses; Influenza-like illness; Severe acute respiratory infections
Contributor Information
Wang Huanru
Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China
Mou Jiabin
Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China
Qiu Qi
Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China
Liu Jiajing
Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China
Yuan Fang
Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China
Liu Meihua
Fengxian District Center for Disease Control and Prevention, Shanghai 201499, China
Tang Xiaode
Baoshan District Center for Disease Control and Prevention, Shanghai 201901, China.
Zhang Jingyi
Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China
Chen Jian
Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China
Chen Min
Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China
Wu Huanyu
Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China
Teng Zheng
Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China
