Original Article
Real-World Study on Myopia Prevention and Control Effects of Defocus Incorporated Multiple Segments Lenses
Qing Zhang, Ling Wang, Guomin Ruan, Tingting Zhou, Xiaomin Gao, Wenli Yu
Published 2024-09-25
Cite as Chin J Optom Ophthalmol Vis Sci, 2024, 26(9): 671-676. DOI: 10.3760/cma.j.cn115909-20240407-00104
Abstract
Objective:To evaluate the effect of defocus incorporated multiple segments (DIMS) lenses on myopia control in children and adolescents in the real-world.
Methods:This was a retrospective observational study. From July 2021 to August 2023, 179 myopia children and adolescents aged 6-12 years were enrolled and prescribed DIMS lens in the Ophthalmology Department of Nanjing Tongren Hospital Affiliated to Southeast University School of Medicine. Participants were divided into low (105 cases), moderate (66 cases), and high myopia (8 cases) groups based on their initial degree of myopia. Follow-up examinations were completed at 6 and 12 months. A refractive development profile was also established. Axial length (AL), refractive power, astigmatism, corneal astigmatism, etc. were measured at each follow-up time point after wearing the DIMS lenses. The Kruskal-Wallis test was used to compare the differences in spherical equivalent (SE) change and AL growth between different myopia groups, and the response rate was used to analyze the degree of myopia and AL changes. The Wilcoxon signed-rank test was used to analyze the changes in astigmatism and corneal astigmatism during the use of DIMS lenses.
Results:There was no significant difference in the increase of myopia (H=1.03, P=0.599) and AL (H=0.16, P=0.923) among the low-myopia, moderate-myopia and high-myopia groups after wearing DIMS lenses for 12 months. At 12 months, 54.2% of patients responded well (myopia increased ≤0.25 D) and 26.8% responded poorly (myopia increased ≥0.75 D). The proportion of patients with 12-month controlled AL length (AL increase ≤0.20 mm) was 41.3%, while 17.9% showed poor AL control response (AL growth >0.40 mm). There were statistically significant differences in astigmatism and corneal astigmatism between children and adolescents after 6 and 12 months of wearing DIMS lenses (P<0.05). However, the influence of confounding factors such as AL growth during use could not be ruled out.
Conclusions:Wearing DIMS lenses is effective in controlling myopia in adolescents and children. Both refractive power and AL were well controlled within one year.
Key words:
myopia; defocus-incorporated multiple segments lenses; myopia control; axial length; children and adolescents; real-world study
Contributor Information
Qing Zhang
Ophthalmology Department, Nanjing Tongren Hospital, School of Medicine, Southeast University, Nanjing 210000, China
Ling Wang
Jinling Institute of Technology, Faculty of Materials Engineering, Nanjing 211169, China
Guomin Ruan
Ophthalmology Department, Nanjing Tongren Hospital, School of Medicine, Southeast University, Nanjing 210000, China
Tingting Zhou
Ophthalmology Department, Nanjing Tongren Hospital, School of Medicine, Southeast University, Nanjing 210000, China
Xiaomin Gao
Ophthalmology Department, Nanjing Tongren Hospital, School of Medicine, Southeast University, Nanjing 210000, China
Wenli Yu
Ophthalmology Department, Nanjing Tongren Hospital, School of Medicine, Southeast University, Nanjing 210000, China
