Original Article
An analysis on clinical characteristics and prognosis of obstructive and non-obstructive hypertrophic cardiomyopathy
Li Yao, Huang Wei, Xu Biao
Published 2018-02-05
Cite as Chin J Postgrad Med, 2018, 41(2): 136-139. DOI: 10.3760/cma.j.issn.1673-4904.2018.02.011
Abstract
ObjectiveTo study the clinical characteristics and prognosis of patients with obstructive hypertrophic cardiomypathy (OHCM) and non-obstructive hypertrophic cardiomypathy(NOHCM).
MethodsA consecutive cohort of patients with hypertrophic cardiomypathy (HCM) were divided into OHCM group and NOHCM group. Clinical data were collected to analyze.
ResultsTwo hundred and six patients were at the mean age of (61.16 ± 13.04) years, 49 patients were in OHCM group and 157 patients were in NOHCM group. The proportion of male in OHCM group was lower than that in NOHCM group: 44.9% (22/49) vs.69.4%(109/157), the onset of syncope in OHCM group was higher than that in NOHCM group: 12.2%(6/49) vs. 3.8% (6/157), there were significant differences (P<0.01 or<0.05). The levels of left ventricular ejection fraction, left ventricular posterior wall thickness and maximum thickness of ventricular wall in two groups had significant differences (P<0.01 or<0.05). During a median follow-up (32 ± 10) months, 21 patients died. Sudden cardiac death was more often observed in OHCM group: 6.1%(3/49) vs. 0.6% (1/157),P<0.05, but there were no significant differences in all-cause mortality, readmission rate and heart failure between two groups (P > 0.05).
ConclusionsThere are some differences on the clinical characteristics between the OHCM patients and NOHCM patients, but the prognosis of NOHCM patients is not better than that of OHCM patients.
Key words:
Cardiomyopathy, hypertrophic; Clinical characteristics; Prognosis; Comparative study
Contributor Information
Li Yao
Department of Cardiovascular, Drum Tower Clinical Medical College of Nanjing Medical University, Nanjing 210008, China
Huang Wei
Xu Biao
