Review
Current status and advances in diagnosis and treatment of solid pseudopapillary neoplasm of the pancreas
Liu Zhengtao, Guo Chengxiang, Yu Jian, Bai Xueli, Liang Tingbo
Published 2020-04-20
Cite as Chin J Dig Surg, 2020, 19(4): 444-448. DOI: 10.3760/cma.j.cn115610-20200410-00249
Abstract
Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare pancreatic tumor with low-grade malignancy. Surgical resection is the preferred therapeutic approach for SPN patients, which has favourable prognosis with extremely low incidence of recurrence and metastasis and 5-year survival rate as 95%. With the improvement of radiological and pathological diagnosis, the detection rate of SPN is increasing. However, its pathogenesis is still unclear. Meanwhile, the diagnostic criteria and treatment strategies of SPN require standardization. Herein, the authors review the current status and advances in SPN based on related literature and clinical experience of the authors′ team on treatment of SPN, in order to deepen the knowledge of SPN, improve the ability for the preoperative diagnosis, promote standardized treatment and maximize benefits of the patients.
Key words:
Pancreatic neoplasms; Solid pseudopa-pillary neoplasm of the pancreas; Pathogenesis; Diagnosis; Therap; Advances
Contributor Information
Liu Zhengtao
Department of Heptobiliary and Pancreatic Surgery, the First Affiliated Hospital of Medical School of Zhejiang University, Zhejiang Provincial Key Laboratory of Pancreatic Disease, Zhejiang Provincial Research Center for Diagnostic and Treatment Techniques for Severe Pancreatic Diseases, Clinical Research Center of Heptobiliary and Pancreatic Diseases of Zhejiang Province, Hangzhou 310003, China
Guo Chengxiang
Department of Heptobiliary and Pancreatic Surgery, the First Affiliated Hospital of Medical School of Zhejiang University, Zhejiang Provincial Key Laboratory of Pancreatic Disease, Zhejiang Provincial Research Center for Diagnostic and Treatment Techniques for Severe Pancreatic Diseases, Clinical Research Center of Heptobiliary and Pancreatic Diseases of Zhejiang Province, Hangzhou 310003, China
Yu Jian
Department of Heptobiliary and Pancreatic Surgery, the First Affiliated Hospital of Medical School of Zhejiang University, Zhejiang Provincial Key Laboratory of Pancreatic Disease, Zhejiang Provincial Research Center for Diagnostic and Treatment Techniques for Severe Pancreatic Diseases, Clinical Research Center of Heptobiliary and Pancreatic Diseases of Zhejiang Province, Hangzhou 310003, China
Bai Xueli
Department of Heptobiliary and Pancreatic Surgery, the First Affiliated Hospital of Medical School of Zhejiang University, Zhejiang Provincial Key Laboratory of Pancreatic Disease, Zhejiang Provincial Research Center for Diagnostic and Treatment Techniques for Severe Pancreatic Diseases, Clinical Research Center of Heptobiliary and Pancreatic Diseases of Zhejiang Province, Hangzhou 310003, China
Liang Tingbo
Department of Heptobiliary and Pancreatic Surgery, the First Affiliated Hospital of Medical School of Zhejiang University, Zhejiang Provincial Key Laboratory of Pancreatic Disease, Zhejiang Provincial Research Center for Diagnostic and Treatment Techniques for Severe Pancreatic Diseases, Clinical Research Center of Heptobiliary and Pancreatic Diseases of Zhejiang Province, Hangzhou 310003, China