Original Article
Status and correlates of sleep quality in schizophrenia inpatients
Chen Yun, Zhang Lüfeng, Zhang Hongle, Wang Di, Zhang Qiufu, Chen Rao, Chu Zhi, Hu Sifan, Sun Hongqiang
Published 2022-05-20
Cite as Chin J Health Manage, 2022, 16(5): 318-324. DOI: 10.3760/cma.j.cn115624-20220219-00114
Abstract
ObjectiveTo explore the status and correlates of sleep quality in hospitalized patients with schizophrenia.
MethodsA total number of 269 schizophrenia inpatients were recruited from 7 hospitals including Peking University Sixth Hospital, Zhumadian Second People′s Hospital and Liaocheng Fourth People′s Hospital from August 2019 to March 2021. The Brief Psychiatric Rating Scale (BPRS), the Pittsburgh Sleep Quality Index (PSQI), the 9-item Patient Health Questionnaire (PHQ-9), the 7-item Generalized Anxiety Disorder Scale (GAD-7) and the suicide module of Mini-International Neuropsychiatric Interview were evaluated. Poor sleep quality was determined by the score of more than 5 according to PSQI, all patients were divided into groups of poor and normal sleep quality. The general demographic data and clinical characteristics of two groups were compared, and the correlates of sleep quality were obtained by Spearman correlations and multiple logistic regression.
ResultsThe prevalence of poor sleep quality in schizophrenia inpatients was up to 44.6% (120/269). Compared with normal sleep quality group, inpatients with poor sleep quality had higher rates of alcohol consumption history, use of benzodiazepines (BZDs) and current suicide risk, and BPRS total score, factor scores (thinking disorders, anxious-depression, hostile-suspiciousness and activation), PHQ-9 and GAD-7 scores were also higher (all P<0.05). Spearman correlation analyses showed that PSQI total score were significantly positively correlated with BPRS total score (r=0.323), PHQ-9 score (r=0.553), GAD-7 score (r=0.456) and current suicide risk level (r=0.320) (all P<0.001). Multiple logistic regression showed that history of alcohol consumption (OR=2.897, 95%CI: 1.002-8.372), use of BZDs (OR=3.181, 95%CI: 1.548-6.534), thinking disorders (OR=1.563, 95%CI: 1.015-2.406), comorbidity with depression (OR=4.968, 95%CI: 1.869-13.202), and current suicide risk (OR=2.496, 95%CI: 1.360-4.581) were independently correlated with poor sleep quality (all P<0.05).
ConclusionPoor sleep quality is common in hospitalized patients with schizophrenia, and history of alcohol consumption, use of BZDs, thinking disorders, comorbidity with depression and current suicide risk are independent correlates of poor sleep quality.
Key words:
Schizophrenia; Sleep quality; Psychiatric symptom; Suicide
Contributor Information
Chen Yun
Peking University Sixth Hospital, NHC Key Laboratory of Mental Health, National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing 100191, China
Zhang Lüfeng
Zhumadian Second People′s Hospital, Zhumadian 463000, China
Zhang Hongle
Liaocheng Fourth People′s Hospital, Liaocheng 252000, China
Wang Di
Beijing Changping Hospital of Integrated Chinese and Western Medicine, Beijing 102208, China
Zhang Qiufu
Beijing Tongzhou Psychiatric Hospital, Beijing 101101, China
Chen Rao
Beijing Chaoyang Third Hospital, Beijing 100121, China
Chu Zhi
Beijing Xicheng District Ping′an Hospital, Beijing 100035, China
Hu Sifan
Peking University Sixth Hospital, NHC Key Laboratory of Mental Health, National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing 100191, China
Sun Hongqiang
Peking University Sixth Hospital, NHC Key Laboratory of Mental Health, National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing 100191, China
