Original Article
Relationship between the blood test results of thyroid function and intolerance to 14 kinds of foods in physical examination population
Chen Zhilai, Huang Zhen, Wang Chengwei, Liu Hongying, Liu Guixia, Zheng Yansong
Published 2022-11-20
Cite as Chin J Health Manage, 2022, 16(11): 781-786. DOI: 10.3760/cma.j.cn115624-20220131-00076
Abstract
ObjectiveTo investigate the relationship between the blood test results of seven items of thyroid function and intolerance to 14 kinds of foods in physical examination population.
MethodsTotal of 45 764 participants who received physical examination and accepted 14-kind food intolerance and 7-item thyroid function detection from August 2016 to September 2019 in Chinese People′s Liberation Army General Hospital were included in this study. The data were analyzed based on age, gender, body mass index, smoking and drinking status, and laboratory test indexes. Chi square test and univariate or multivariate logistic regression were applied to analyze the correlation between food intolerance and thyroid function in the physical examination population.
ResultsIn the subjects, there were 29 361 cases (64.16%) with at least intolerance to one kind of food, and 15 011 (32.80%) were in Grade 1, 9 037 (19.75%) in grade 2 and 5 313 (11.61%) in grade 3. The positive rate of egg intolerance was the highest (34.06%), and that of beef intolerance was the lowest (1.24%). Of the participants, 11 337 (24.77%) had at least one item thyroid dysfunction, among them, the highest abnormal rate was found in thyroid stimulating hormone (TSH), followed by anti-thyroglobulin antibodies and anti-thyroid peroxidase antibodies. The proportion (26.32%) of abnormal thyroid function in the participants with at least intolerance to one kind of food was significantly higher than that (22.00%) in the participants without intolerance to the 14 kinds of foods (χ2=105.78, P<0.001). After adjusting for other significantly related factors, the positive results of intolerance to 14 kinds of foods was still the significant influencing factor of thyroid function abnormalities (OR=1.14, Z=5.68, 95%CI: 1.09-1.20, P<0.001). Further analysis showed that, after adjusted for age, gender, smoking and drinking status, intolerance to four kinds of foods (egg, soybean, crab and pork) were the significant influencing factors of abnormal thyroid function.
ConclusionsFood intolerance is an independent risk factor of thyroid dysfunction. Among them, egg, soybean, crab and pork may be the most important food varieties should be paid more attention to.
Key words:
Food intolerance; Risk factors; Cohort study; Health management; Thyroid function
Contributor Information
Chen Zhilai
Deparment of Health Medicine, the Second Medical Center &
National Clinical Research Center for Geriatric Diseases, Chinese People′s Liberation Army General Hospital, Beijing 100853, China
Huang Zhen
Health Management Center, Nanning First People′s Hospital (the Fifth Clinical Medical College of Guangxi Medical University), Nanning 530022, China
Wang Chengwei
Deparment of Health Medicine, the Second Medical Center &
National Clinical Research Center for Geriatric Diseases, Chinese People′s Liberation Army General Hospital, Beijing 100853, China
Liu Hongying
Deparment of Health Medicine, the Second Medical Center &
National Clinical Research Center for Geriatric Diseases, Chinese People′s Liberation Army General Hospital, Beijing 100853, China
Liu Guixia
Deparment of Health Medicine, the Second Medical Center &
National Clinical Research Center for Geriatric Diseases, Chinese People′s Liberation Army General Hospital, Beijing 100853, China
Zheng Yansong
Deparment of Health Medicine, the Second Medical Center &
National Clinical Research Center for Geriatric Diseases, Chinese People′s Liberation Army General Hospital, Beijing 100853, China
