To analyze the potential influencing factors of depression among chronic heart failure (CHF) patients systematically, so as to provide reference for effective intervention.

We searched the databases of CNKI, WanFang Data, VIP, CBM, PubMed, Cochrane library, Web of Science, Embase, PsycINFO and PsyARTICLE database for relevant articles. The literature was screened according to the inclusion and exclusion criteria. The quality of the included literature was evaluated and the data was extracted by 2 researchers independently. Review Manager 5.3 was used to analyze the data.

A total of 25 articles were included. The combined effect size OR/SD (95%CI) of each influencing factor in descending order were: sedentary behavior 2.75 (1.62 to 4.66) , long duration 2.58 (2.09 to 3.07) , EF values -2.29 (-3.44 to -1.13) , NYHAⅢ/Ⅳ 2.28 (1.70 to 3.08) , the combination of anemia 1.72 (1.30 to 2.28) , solitary 1.48 (1.16 to 1.88) , the combination of Chronic renal insufficiency 1.46 (1.16 to 1.85) and COPD 1.44 (1.04 to 2.00) , low BMI -1.13 (-1.64 to -0.98) , good knowledge of heart failure 0.67 (0.47 to 0.95) , male 0.63 (0.53 to 0.76) , married 0.57 (0.47 to 0.69) .

The influencing factors of chronic heart failure combined with depression are diverse. Medical staff can identify the heart failure patients with high prevalence of depression early according to the related influencing factors, and can also intervene the controllable influencing factors to reduce the occurrence of depression.

Heart failure; Depression; Influencing factors; Meta-analysis